Recombinant Human GDNF Family Receptor Alpha 1

• Catalog number
  MBS147053
• Price
  Please ask
• Size
  0.01 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [GDNF Family Receptor Alpha 1]
• Products_name_syn
  [GDNF receptor alpha-1; GDNFR-alpha-1; GFRalpha-1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1; GDNFRA1; RET1L2; RETL1; Glial Cell LineDerived Neurotrophic Factor Receptor Alpha; TRNR1; GPILinked Anchor Protein; PI-Linked Cell-Surface; GFRA1 Human; GDNF Family Receptor Alpha 1 Human Recombinant]
• Other_names
  [GDNF family receptor alpha-1; GDNF family receptor alpha-1; GDNF family receptor alpha-1; GDNF family receptor alpha 1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1]
• Products_gene_name
  [GFRA1]
• Other_gene_names
  [GFRA1; GFRA1; GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1; GDNFRA; RETL1; TRNR1; GDNF receptor alpha-1; GDNFR-alpha-1; GFR-alpha-1]
• Purity
  Greater than 95.0% as determined by SDS-PAGE
• Form
  Filtered white lyophilized (freeze-dried) powderGFRA1 filtered (0.4 um) and lyophilized from 0.5mg/ml in phosphate buffered saline pH 7.5 containing 5 % (w/v) trehalose
• Storage_stability
  Store lyophilized protein at-20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C
• Description
  The Recombinant GDNF Family Receptor Alpha 1 is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  GDNF   Family   Receptor   Alpha  
• Gene symbol
  GDNF, GDNF-AS1
• Short name
  Recombinant GDNF Family Receptor Alpha 1
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  HEK293 cells
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens glial cell derived neurotrophic factor family Receptor a 1
• Alternative technique
  rec
• Alternative to gene target
  glial cell derived neurotrophic factor, ATF1 and ATF2 and HFB1-GDNF and HSCR3, GDNF and IDBG-17169 and ENSG00000168621 and 2668, protein homodimerization activity, Extracellular, Gdnf and IDBG-128378 and ENSMUSG00000022144 and 14573, BT.58072 and IDBG-630047 and ENSBTAG00000005176 and 386587

Gene info

• Identity
  HGNC:4232
• Gene
  GDNF
• Long gene name
  glial cell derived neurotrophic factor
• Synonyms
  • ATF1
  • ATF2
  • HFB1-GDNF
• Synonyms name
  • astrocyte-derived trophic factor
  • glial cell line derived neurotrophic factor
  • glial derived neurotrophic factor
• Locus
  5p13.2
• Discovery year
  1995-05-04
• Entrez gene record
  2668
• Pubmed identfication
  • 8493557
• RefSeq identity
  • NM_000514
• Classification
  • GDNF family ligands
• VEGA ID
  OTTHUMG00000090809

Gene info

• Identity
  HGNC:43592
• Gene
  GDNF-AS1
• Long gene name
  GDNF antisense RNA 1
• Synonyms gene name
  • GDNF antisense RNA 1 (non-protein coding)
  • GDNF antisense RNA 1
  • GDNF antisense RNA 1 (head to head)
• Synonyms
  • GDNFOS
• Synonyms name
  • GDNF opposite strand
• GenBank acession
  • DA359107
• Locus
  5p13.2
• Discovery year
  2011-11-16
• Entrez gene record
  100861519
• Pubmed identfication
  • 22081608
• RefSeq identity
  • NR_103441
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162110

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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