Human GDNF family receptor alpha-like (GFRAL)

  • Catalog number
    CSB-EP751020HUb1-50ug
  • Price
    Please ask
  • Size
    50ug
  • Description
    Recombinant Human GDNF family receptor alpha-like(GFRAL),partial expressed in E.coli
  • Specifications
    Uniprot ID: Q6UXV0; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 19-351aa; Sequence information: Extracellular Domain; Tag: N-terminal 10xHis-tagged and C-terminal Myc-tagged; Purity: Greater than 85% as determined by SDS-PAGE.
  • Additional_information
    MW: 42.8 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
  • Storage_and_shipping
    Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
  • Notes
    For research use only.
  • Additional description
    The GDNF family receptor alpha-like (GFRAL) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Gene target
  • Gene symbol
    GDNF, GDNF-AS1, GFRAL
  • Short name
    GDNF family receptor alpha-like (GFRAL)
  • Species
    Human, Humans
  • Alternative name
    H. sapiens glial cell derived neurotrophic factor family receptor a-like (glial cell derived neurotrophic factor family receptor alpha like)
  • Alternative to gene target
    glial cell derived neurotrophic factor, ATF1 and ATF2 and HFB1-GDNF and HSCR3, GDNF and IDBG-17169 and ENSG00000168621 and 2668, protein homodimerization activity, Extracellular, Gdnf and IDBG-128378 and ENSMUSG00000022144 and 14573, BT.58072 and IDBG-630047 and ENSBTAG00000005176 and 386587
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