Recombinant Human GDNF Family Receptor Alpha 1
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Catalog number
MBS147053
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Price
Please ask
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Size
1 mg
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Products_type
Recombinant Protein
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Products_short_name
[GDNF Family Receptor Alpha 1]
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Products_name_syn
[GDNF receptor alpha-1; GDNFR-alpha-1; GFRalpha-1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1; GDNFRA1; RET1L2; RETL1; Glial Cell LineDerived Neurotrophic Factor Receptor Alpha; TRNR1; GPILinked Anchor Protein; PI-Linked Cell-Surface; GFRA1 Human; GDNF Family Receptor Alpha 1 Human Recombinant]
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Other_names
[GDNF family receptor alpha-1; GDNF family receptor alpha-1; GDNF family receptor alpha-1; GDNF family receptor alpha 1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1]
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Products_gene_name
[GFRA1]
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Other_gene_names
[GFRA1; GFRA1; GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1; GDNFRA; RETL1; TRNR1; GDNF receptor alpha-1; GDNFR-alpha-1; GFR-alpha-1]
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Purity
Greater than 95.0% as determined by SDS-PAGE
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Form
Filtered white lyophilized (freeze-dried) powderGFRA1 filtered (0.4 um) and lyophilized from 0.5mg/ml in phosphate buffered saline pH 7.5 containing 5 % (w/v) trehalose
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Storage_stability
Store lyophilized protein at-20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C
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Description
The Recombinant GDNF Family Receptor Alpha 1 is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
GDNF, GDNF-AS1
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Short name
Recombinant GDNF Family Receptor Alpha 1
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
HEK293 cells
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Species
Human, Humans
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Alternative name
Rec. H. sapiens glial cell derived neurotrophic factor family Receptor a 1
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Alternative technique
rec
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Alternative to gene target
glial cell derived neurotrophic factor, ATF1 and ATF2 and HFB1-GDNF and HSCR3, GDNF and IDBG-17169 and ENSG00000168621 and 2668, protein homodimerization activity, Extracellular, Gdnf and IDBG-128378 and ENSMUSG00000022144 and 14573, BT.58072 and IDBG-630047 and ENSBTAG00000005176 and 386587
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Gene info
Gene info
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Identity
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Gene
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Long gene name
GDNF antisense RNA 1
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Synonyms gene name
- GDNF antisense RNA 1 (non-protein coding)
- GDNF antisense RNA 1
- GDNF antisense RNA 1 (head to head)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2011-11-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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