RAT ANTI MOUSE CD16

• Catalog number
  MBS224798
• Price
  Please ask
• Size
  0.25 mg

• Products_type
  Antibody
• Products_short_name
  [CD16]
• Products_name_syn
  [FcRIII]
• Other_names
  [Low affinity immunoglobulin gamma Fc region receptor III; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III; Fc receptor, IgG, low affinity III; Fc-gamma RIII; FcRIII; CD_antigen: CD16]
• Products_gene_name
  [CD16]
• Other_gene_names
  [Fcgr3; Fcgr3; CD16; IgG Fc receptor III; FcRIII]
• Clonality
  Monoclonal
• Clone
  [AT154-2]
• Specificity
  Rat anti Mouse CD16 anitbody, clone AT154-2, recognizes CD16, also known as FcRIII. CD16 is a low affiniity activatory receptor which interacts preferentially with mouse IgG1, IgG2a and IgG2b immune complexes and is involved in various effector functions including phagocytosis, NK antibody dependent cellular cytotoxicity and the release of inflammatory mediators. In mice, CD16 is expressed on macrophages, NK cells, granulocytes, myeloid precursors and subpopulations of T lymphocytes.
• Form
  Purified IgG - liquid, TRIS buffered saline
• Storage_stability
  Shelf Life: 18 months form date of dispatch. Store at 4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
• Tested_application
  Flow Cytometry (FC), Immunohistology - Frozen
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

• Gene target
  CD16  
• Gene symbol
  FCGR3A, FCGR3B
• Short name
  ANTI MOUSE CD16
• Technique
  anti mouse, Mouse, anti, antibody to, anti mouse antibodies, mouses
• Host
  Rat
• Isotype
  IgG2b
• Species
  Mouse, Mouses, Rats
• Alternative name
  RAT antibody to MOUSE CD16
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:3619
• Gene
  FCGR3A
• Long gene name
  Fc gamma receptor IIIa
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Fc fragment of IgG receptor IIIa
• Synonyms
  • CD16
  • CD16a
  • FcgammaRIIIa
  • FcGRIIIA
• GenBank acession
  • BC036723
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2214
• Pubmed identfication
  • 2139735
  • 11835346
  • 19309690
• RefSeq identity
  • NM_000569
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034466
• Locus Specific Databases
  • FCGR3Abase: Mutation registry for Natural killer cell deficiency
  • LRG_60

Gene info

• Identity
  HGNC:3620
• Gene
  FCGR3B
• Long gene name
  Fc gamma receptor IIIb
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Fc fragment of IgG receptor IIIb
• Synonyms
  • CD16
  • CD16b
  • FcgammaRIIIb
  • FcRIIIb
• GenBank acession
  • J04162
• Locus
  1q23.3
• Discovery year
  1991-08-21
• Entrez gene record
  2215
• Pubmed identfication
  • 2139735
  • 11034564
  • 17529978
• RefSeq identity
  • NM_000570
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000074099
• Locus Specific Databases
  • LRG_1238

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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