MOUSE ANTI HUMAN CD16

• Catalog number
  MBS212047
• Price
  Please ask
• Size
  0.2 mg

• Products_type
  Antibody
• Products_short_name
  [CD16]
• Products_name_syn
  [CD16A, CD16B, FCG3, FCGR3, IGFR3, FcRIII]
• Other_names
  [low affinity immunoglobulin gamma Fc region receptor III-B isoform 2; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma receptor IIIb (CD 16); fc-gamma RIII-beta; fc-gamma RIIIb; igG Fc receptor III-1; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD_antigen: CD16b]
• Products_gene_name
  [CD16]
• Other_gene_names
  [FCGR3B; FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb; CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb]
• Clonality
  Monoclonal
• Clone
  [LNK16]
• Specificity
  Mouse anti Human CD16 antibody, clone LNK16 recognizes CD16, a 50-65kDa cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Mouse anti Human CD16 antibody, clone LNK16 has been reported to block the binding of IgG to the CD16 molecule (Tamm and Schmidt 1996).
• Form
  Purified IgG - liquid
• Concentration
  IgG concentration 1.0 mg/ml
• Storage_stability
  Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
• Tested_application
  Flow cytometry (FC/FACS), Immunoprecipitation (IP)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  CD16  
• Gene symbol
  FCGR3A, FCGR3B
• Short name
  MOUSE ANTI CD16
• Technique
  anti human, Mouse, anti, antibody to, anti human antibodies, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  MOUSE antibody to H. sapiens CD16
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:3619
• Gene
  FCGR3A
• Long gene name
  Fc gamma receptor IIIa
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Fc fragment of IgG receptor IIIa
• Synonyms
  • CD16
  • CD16a
  • FcgammaRIIIa
  • FcGRIIIA
• GenBank acession
  • BC036723
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2214
• Pubmed identfication
  • 2139735
  • 11835346
  • 19309690
• RefSeq identity
  • NM_000569
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034466
• Locus Specific Databases
  • FCGR3Abase: Mutation registry for Natural killer cell deficiency
  • LRG_60

Gene info

• Identity
  HGNC:3620
• Gene
  FCGR3B
• Long gene name
  Fc gamma receptor IIIb
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Fc fragment of IgG receptor IIIb
• Synonyms
  • CD16
  • CD16b
  • FcgammaRIIIb
  • FcRIIIb
• GenBank acession
  • J04162
• Locus
  1q23.3
• Discovery year
  1991-08-21
• Entrez gene record
  2215
• Pubmed identfication
  • 2139735
  • 11034564
  • 17529978
• RefSeq identity
  • NM_000570
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000074099
• Locus Specific Databases
  • LRG_1238

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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