Rabbit Polyclonal to Human TMPO / TP / Thymopoietin

• Catalog number
  MBS248731
• Price
  Please ask
• Size
  0,05 mg

• Other size
  please contact us to order other different size
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• Gene
  Thymopoietin I and II are proteins involved in the induction of CD90 in the thymus. The thymopoetin (TMPO) gene encodes three alternatively spliced mRNAs encoding proteins of 75 kDa (alpha), 51 kDa (beta) and 39 kDa (gamma) which are ubiquitously expressed in all cells. The human TMPO gene maps to chromosome band 12q22 and consists of eight exons. TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane. TMPO beta is a human homolog of the murine protein LAP2. LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes. This interaction is regulated by phosphorylation during mitosis. Given the nuclear localization of the three TMPO isoforms, it is unlikely that these proteins play any role in CD90 induction.

• Gene target
  TMPO   Thymopoietin  
• Gene symbol
  TMPO-AS1, TMPO
• Short name
  Rabbit Polyclonal TMPO / TP / Thymopoietin
• Technique
  Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Species
  Human, Humans
• Alternative name
  production species: rabbit polyclonal to H. sapiens TMPO / TP / Thymopoietin
• Alternative technique
  polyclonals, rabbit-anti

Gene info

• Identity
  HGNC:44158
• Gene
  TMPO-AS1
• Long gene name
  TMPO antisense RNA 1
• Synonyms gene name
  • TMPO antisense RNA 1 (non-protein coding)
• Locus
  12q23.1
• Discovery year
  2012-06-30
• Entrez gene record
  100128191
• Pubmed identfication
  • 31230752
• RefSeq identity
  • NR_027157
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000170209

Gene info

• Identity
  HGNC:11875
• Gene
  TMPO
• Long gene name
  thymopoietin
• Synonyms
  • TP
  • LAP2
  • LEMD4
• Synonyms name
  • LEM domain containing 4
• Locus
  12q23.1
• Discovery year
  1994-11-08
• Entrez gene record
  7112
• Pubmed identfication
  • 7517549
• RefSeq identity
  • NM_003276
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000170210
• Locus Specific Databases
  • LRG_443

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