RABBIT ANTI RAT GLUTAMATE RECEPTOR 1 (C-TERMINAL)

• Catalog number
  MBS220876
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [GluR1]
• Other_names
  [glutamate receptor 1; Glutamate receptor 1; glutamate receptor 1; AMPA-selective glutamate receptor 1; GluR1; gluR-1; gluR-K1; glutamate receptor A; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA1 (alpha 1); glutamate receptor, ionotropic, AMPA 1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; GluA1]
• Other_gene_names
  [Gria1; Gria1; GluA1; gluR-A; Glur1; GluR-1; GluA1]
• Clonality
  Polyclonal
• Reactivity
  Hamster, Human, Monkey
• Specificity
  This item recognises the glutamate receptor 1 (also known as AMPA) which acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.This antibody linked to immobilized Protein A immunoprecipitates detergent-solubilized receptor from brain or transfected cells.
• Form
  Purified Purified Ig - liquid
• Concentration
  Ig concentration 1 mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
• Tested_application
  Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Oryctolagus cuniculus, Rattus norvegicus

• Gene target
  GLUTAMATE   RECEPTOR  
• Gene symbol
  GRIK1, GRIP1, GRID1
• Short name
  RABBIT ANTI GLUTAMATE RECEPTOR 1 (C-TERMINAL)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Rat, Rats
• Alternative name
  production species: rabbit antibody to RAT GLUTAMATE RECEPTOR 1 (C-TERMINAL)
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:4579
• Gene
  GRIK1
• Long gene name
  glutamate ionotropic receptor kainate type subunit 1
• Synonyms gene
  • GLUR5
• Synonyms gene name
  • glutamate receptor, ionotropic, kainate 1
• Synonyms
  • GluK1
• Locus
  21q21.3
• Discovery year
  1992-02-26
• Entrez gene record
  2897
• Pubmed identfication
  • 8468067
• Classification
  • Glutamate ionotropic receptor kainate type subunits
• VEGA ID
  OTTHUMG00000078879

Gene info

• Identity
  HGNC:18708
• Gene
  GRIP1
• Long gene name
  glutamate receptor interacting protein 1
• GenBank acession
  • AJ133439
• Locus
  12q14.3
• Discovery year
  2002-05-29
• Entrez gene record
  23426
• Pubmed identfication
  • 10197531
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000169019

Gene info

• Identity
  HGNC:4575
• Gene
  GRID1
• Long gene name
  glutamate ionotropic receptor delta type subunit 1
• Synonyms gene name
  • glutamate receptor, ionotropic, delta 1
• Synonyms
  • GluD1
  • KIAA1220
• GenBank acession
  • AB033046
• Locus
  10q23.1-q23.2
• Discovery year
  1997-10-21
• Entrez gene record
  2894
• RefSeq identity
  • NM_017551
• Classification
  • Glutamate ionotropic receptor delta type subunits
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000018650

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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