RABBIT ANTI RAT METABOTROPIC GLUTAMATE RECEPTOR 1a
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Catalog number
MBS224070
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Price
Please ask
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Size
0.1 mL
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Products_type
Antibody
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Products_short_name
[METABOTROPIC GLUTAMATE RECEPTOR 1a]
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Other_names
[metabotropic glutamate receptor 1 isoform beta; Metabotropic glutamate receptor 1; metabotropic glutamate receptor 1; G protein coupled receptor family C group 1 member A; mGluR1; glutamate receptor, metabotropic 1]
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Other_gene_names
[Grm1; Grm1; Gprc1a; Gprc1a; Mglur1; mGluR1]
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Clonality
Polyclonal
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Specificity
This item recognises rat metabotropic glutamate receptor 1a (mGluR1a). The metabotropic glutamate receptors have been organised into three groups. mGluR5 and mGluR1 make up group I which, when activated, stimulates phospholipase C and activates protein kinase C to hydrolyse phosphoinositide phospholipids in the cell membrane. Group I mGluRs, but not other groups, are activated by 3, 5-dihydroxyphenylglycine (DHPG).
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Form
Purified Purified IgG - liquid
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Storage_stability
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
Immunohistology Frozen, Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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About
Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Oryctolagus cuniculus, Rattus norvegicus
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Gene target
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Short name
RABBIT ANTI METABOTROPIC GLUTAMATE RECEPTOR 1a
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Technique
Rabbit, anti, antibody to
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Host
Rabbit, Rabbits
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Isotype
IgG
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Species
Rat, Rats
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Alternative name
production species: rabbit antibody to RAT METABOTROPIC GLUTAMATE RECEPTOR 1a
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Alternative technique
rabbit-anti, antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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