RABBIT ANTI MOUSE FLIP (C-TERMINAL)

• Catalog number
  MBS221590
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [FLIP L]
• Other_names
  [CASP8 and FADD-like apoptosis regulator isoform 1; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; FADD-like antiapoptotic molecule 1; MACH-related inducer of toxicity; caspase homolog; caspase-eight-related protein; caspase-like apoptosis regulatory protein; cellular FLICE-like inhibitory protein; inhibitor of FLICE; usurpin; CASP8 and FADD-like apoptosis regulator; Caspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity; MRIT; UsurpinCleaved into the following 2 chains:CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
• Products_gene_name
  [FLIP]
• Other_gene_names
  [Cflar; Cflar; Cash; Flip; MRIT; CLARP; FLAME; Casper; Gm9845; c-Flip; FLAME-1; I-FLICE; 2310024N18Rik; A430105C05Rik; ENSMUSG00000072980; Cash; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT]
• Clonality
  Polyclonal
• Specificity
  This item recognises the apoptosis related protein designated FLIP (FLICE inhibitory protein).FLIP interacts with the adaptor protein FADD, and with Caspase-8 (FLICE) and Caspase-10 (FLICE2) to inhibit apoptosis induced by death receptors including CD95, DR3, TRAIL-R and TNFR1.FLIP exists in 2 forms, FLIPs (short) and FLIPL (long). This item recognises only FLIPL.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Oryctolagus cuniculus
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

• Gene target
  FLIP  
• Gene symbol
  CFLAR
• Short name
  RABBIT ANTI MOUSE FLIP (C-TERMINAL)
• Technique
  anti mouse, Rabbit, Mouse, anti, antibody to, anti mouse antibodies, mouses
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Mouse, Mouses
• Alternative name
  production species: rabbit antibody to MOUSE FLIP (C-TERMINAL)
• Alternative technique
  rabbit-anti, murine, antibodies

Gene info

• Identity
  HGNC:1876
• Gene
  CFLAR
• Long gene name
  CASP8 and FADD like apoptosis regulator
• Synonyms gene
  • CASP8AP1
• Synonyms gene name
  • CASP8 and FADD-like apoptosis regulator
• Synonyms
  • CASH
  • Casper
  • CLARP
  • FLAME
  • FLIP
  • I-FLICE
  • MRIT
  • c-FLIP
  • cFLIP
• GenBank acession
  • AF005774
• Locus
  2q33.1
• Discovery year
  1999-05-07
• Entrez gene record
  8837
• Pubmed identfication
  • 9208847
  • 9217161
• RefSeq identity
  • NM_003879
• Classification
  • Receptor ligands
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132819

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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