RABBIT ANTI IRE1p (C-TERMINAL)

• Catalog number
  MBS221321
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [IRE1p]
• Other_names
  [serine/threonine-protein kinase/endoribonuclease IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1; ER to nucleus signalling 1; ERN1; endoplasmic reticulum-to-nucleus signaling 1; inositol-requiring 1; inositol-requiring enzyme 1; inositol-requiring protein 1; ire1-alpha; endoplasmic reticulum to nucleus signaling 1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a]
• Products_gene_name
  [IRE1p]
• Other_gene_names
  [ERN1; ERN1; IRE1; IRE1P; IRE1a; hIRE1p; hIRE1p; IRE1a]
• Clonality
  Polyclonal
• Reactivity
  Mouse, Rat
• Specificity
  This item recognises inositol-requiring kinase 1 precursor (IRE1p), a 108kDa serine-threonine kinase/endoribonuclease also known as ERN1. It is an endoplasmic reticulum (ER) transmembrane protein, normally bound to the ER molecular chaperones GRP78 and GRP94. At times of ER stress, due to accumulation of unfolded proteins, IRE1p becomes dissociated from the chaperones, which allows it to activate the un-folded protein transcriptional response (UPR). In the mammalian genome, there are two homologs Ire1alpha and Ire1beta. Ire1alpha is expressed in all cells and tissues, Ire1beta expression is primarily restricted to intestinal epithelial cells.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Immunohistology Frozen, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  IRE1p  
• Gene symbol
  ERN1
• Short name
  RABBIT ANTI IRE1p (C-TERMINAL)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Alternative name
  production species: rabbit antibody to IRE1p (C-TERMINAL)
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:3449
• Gene
  ERN1
• Long gene name
  endoplasmic reticulum to nucleus signaling 1
• Synonyms gene name
  • ER to nucleus signalling 1
• Synonyms
  • IRE1
  • IRE1P
• Synonyms name
  • inositol-requiring enzyme 1
  • Serine/threonine-protein kinase/endoribonuclease IRE1
• GenBank acession
  • AF059198
• Locus
  17q23.3
• Discovery year
  1998-08-06
• Entrez gene record
  2081
• Pubmed identfication
  • 9637683
• RefSeq identity
  • NM_001433
• Classification
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000178879

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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