Rabbit Anti Human ERN1 Antibody-Non-conjugated
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Catalog numberCSB-PA007795LA01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human ERN1, Non-conjugated
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Synonym nameERN1 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDO75460
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant Human Serine/threonine-protein kinase/endoribonuclease IRE1 protein (493-561AA)
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Immunogen speciesHuman
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AliasSerine/threonine-protein kinase/endoribonuclease IRE1,Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a,Serine/threonine-protein kinase,Endoribonuclease,ERN1
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BackgroundSenses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
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ClonalityPolyclonal antibody
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Shipping and storageERN1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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Short name of the antigenSerine/threonine-protein kinase/endoribonuclease IRE1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolERN1
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Short nameAnti-ERN1
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameERN1 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetendoplasmic reticulum to nucleus signaling 1, hIRE1p and IRE1 and IRE1a and IRE1P, ERN1 and IDBG-64539 and ENSG00000178607 and 2081, transferase activity, nuclei, Ern1 and IDBG-213476 and ENSMUSG00000020715 and 78943, ERN1 and IDBG-641835 and ENSBTAG00000016799 and 524719
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Gene info
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Identity
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Gene
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Long gene nameendoplasmic reticulum to nucleus signaling 1
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Synonyms gene name
- ER to nucleus signalling 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-08-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Endoribonucleases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data