RABBIT ANTI HUMAN PPAR ALPHA (N-TERMINAL)
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Catalog number
MBS221542
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Price
Please ask
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Size
0.05 mg
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Products_type
Antibody
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Products_short_name
[PPAR ALPHA]
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Other_names
[peroxisome proliferator-activated receptor alpha; Peroxisome proliferator-activated receptor alpha; peroxisome proliferator-activated receptor alpha; PPAR-alpha; nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor, alpha; peroxisome proliferator-activated nuclear receptor alpha variant 3; peroxisome proliferator-activated receptor alpha; Nuclear receptor subfamily 1 group C member 1]
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Products_gene_name
[PPAR ALPHA]
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Other_gene_names
[PPARA; PPARA; PPAR; NR1C1; hPPAR; PPARalpha; NR1C1; PPAR; PPAR-alpha]
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Clonality
Polyclonal
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Specificity
This item detects an epitope within the N-terminal region of human peroxisome proliferator-activated receptor, alpha (PPARA), a member of the nuclear hormone receptor subfamily. Upon activation, PPARA forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. In particular, PPARA controls genes involved in the peroxisomal and mitochondrial beta oxidation pathways, fatty acid uptake, and triglyceride catabolism in the liver and skeletal muscle. PPARA also has anti-inflammatory and anti-proliferative effects and prevents the proatherogenic effects of cholesterol accumulation in macrophages by stimulating cholesterol efflux. PPARA is the main target of fibrate drugs; hypolipidemic agents used in the treatment of dyslipidemia and the prevention of cardiovascular disease. They could also be used for the treatment of type II diabetes.
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Form
Purified Purified IgG - liquid
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Concentration
IgG concentration 1.0mg/ml
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Storage_stability
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
ELISA (EIA), Western Blot (WB)
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Description
The RABBIT ANTI PPAR ALPHA (N-TERMINAL) is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
PPARA, SRPRA, CBX5, AGPAT1, DRAP1, SCART1, TUBA3D, TLK2, CAMK1, CTNNAL1
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Short name
RABBIT ANTI PPAR ALPHA (N-TERMINAL)
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Technique
anti human, Rabbit, anti, antibody to, anti human antibodies
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Host
Rabbit, Rabbits
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Isotype
IgG
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Species
Human, Humans
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Alternative name
production species: rabbit antibody to H. sapiens PPAR a (N-TERMINAL)
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Alternative technique
rabbit-anti, antibodies
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Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
chromobox 5
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Synonyms gene name
- chromobox homolog 5 (Drosophila HP1 alpha)
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox homolog 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
- MicroRNA protein coding host genes
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
DR1 associated protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-09-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
tubulin alpha 3d
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
tousled like kinase 2
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-01-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
catenin alpha like 1
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Synonyms gene name
- catenin (cadherin-associated protein), alpha-like 1
- catenin alpha-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-12-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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