RABBIT ANTI GLI3

• Catalog number
  MBS222908
• Price
  Please ask
• Size
  5x0.05 mg

• Products_type
  Antibody
• Products_short_name
  [GLI3]
• Other_names
  [transcriptional activator GLI3; Transcriptional activator GLI3; transcriptional activator GLI3; GLI-Kruppel family member GLI3; glioma-associated oncogene family zinc finger 3; oncogene GLI3; zinc finger protein GLI3; GLI family zinc finger 3; GLI3 form of 190 kDa; GLI3-190; GLI3 full length protein; GLI3FL]
• Products_gene_name
  [GLI3]
• Other_gene_names
  [GLI3; GLI3; PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190; GLI3-190; GLI3FL; GLI3-83]
• Clonality
  Polyclonal
• Reactivity
  Amphibia, Chicken, Chimpanzee, Dog, Monkey, Mouse, Quail, Rat
• Specificity
  This item recognizes the Human Zinc Finger protein 3 (GLI-3), also known as GLI-Kruppel family member 3, a 169.8kDa protein belonging to the GLI C2H2-type zinc finger protein of transcription factors. GLI-3 and the related GLI-2 proteins are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse, GLI-2 being primarily a transcriptional activator while GLI-3 is a transcriptional repressor. GLI-3 plays a role in the development of the limbs and brain. It is expressed in a wide range of adult tissues including the colon, lung, spleen, testis and placenta. Defects in GLI3 are causative of a range of disease states including Pallister-Hall syndrome, type IV preaxial polydactyly, acrocallosal syndrome (ACS) and Greig cephalo-poly-syndactyly syndrome. GLI proteins are also implicated as potent oncogenes in the embryonal carcinoma cell.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  GLI3  
• Gene symbol
  GLI3
• Short name
  RABBIT ANTI GLI3
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Alternative name
  production species: rabbit antibody to GLI family zinc finger 3
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  GLI family zinc finger 3, ACLS and GCPS and GLI3-190 and GLI3FL and PAP-A and PAPA and PAPA1 and PAPB and PHS and PPDIV, GLI3 and IDBG-13536 and ENSG00000106571 and 2737, metal ion binding, nuclei, Gli3 and IDBG-131686 and ENSMUSG00000021318 and 14634, GLI3 and IDBG-634502 and ENSBTAG00000010671 and 785371

Gene info

• Identity
  HGNC:4319
• Gene
  GLI3
• Long gene name
  GLI family zinc finger 3
• Synonyms gene
  • GCPS
  • PHS
• Synonyms gene name
  • Greig cephalopolysyndactyly syndrome
  • GLI-Kruppel family member GLI3
  • glioma-associated oncogene family zinc finger 3
• Synonyms
  • PAP-A
  • PAPA
  • PAPA1
  • PAPB
  • ACLS
  • PPDIV
• Synonyms name
  • zinc finger protein GLI3
  • oncogene GLI3
  • DNA-binding protein
• Locus
  7p14.1
• Discovery year
  1989-05-29
• Entrez gene record
  2737
• Pubmed identfication
  • 2118997
• RefSeq identity
  • NM_000168
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000023630

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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