RABBIT ANTI BIM

• Catalog number
  MBS221821
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [BIM]
• Other_names
  [bcl-2-like protein 11 isoform 11; Bcl-2-like protein 11; bcl-2-like protein 11; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; BCL2-like 11 (apoptosis facilitator); Bcl2-interacting mediator of cell death]
• Products_gene_name
  [BIM]
• Other_gene_names
  [BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11]
• Clonality
  Polyclonal
• Reactivity
  Mouse (Expected from Sequence), Rat (Expected from Sequence)
• Specificity
  This item is specific for human Bcl-2 interacting mediator of cell death (Bim), also known as Bod. Bim is a pro-apoptotic protein within the Bcl-2 family, which functions within the intrinsic apotosis pathway. Bim is known to interact with pro-survival proteins including Bcl-2, Bcl-XL and Bcl-w. Bim is expressed in a variety of cell types, where it is maintained in an inactive conformation by phosphorylation or through binding to the microtubule-associated dynein motor complex. Upon certain apoptotic stimuli, Bim is released from microtubules and mediates caspase-dependent apoptosis.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0 mg/ml.
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
• Tested_application
  Immunohistology Paraffin*, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  BIM  
• Gene symbol
  BCL2L11
• Short name
  RABBIT ANTI BIM
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Alternative name
  production species: rabbit antibody to BIM
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:994
• Gene
  BCL2L11
• Long gene name
  BCL2 like 11
• Synonyms gene name
  • BCL2-like 11 (apoptosis facilitator)
• Synonyms
  • BOD
  • BimL
  • BimEL
  • BimS
  • BIM
• GenBank acession
  • AF032458
• Locus
  2q13
• Discovery year
  1999-12-10
• Entrez gene record
  10018
• Pubmed identfication
  • 9731710
  • 9430630
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000131256
• Locus Specific Databases
  • LRG_620

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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