GOAT ANTI HUMAN BIM (C-TERMINAL)
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Catalog number
MBS224109
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Price
Please ask
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Size
0.1 mg
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Products_type
Antibody
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Products_short_name
[BIM]
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Other_names
[bcl-2-like protein 11 isoform 11; Bcl-2-like protein 11; bcl-2-like protein 11; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; BCL2-like 11 (apoptosis facilitator); Bcl2-interacting mediator of cell death]
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Products_gene_name
[BIM]
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Other_gene_names
[BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11]
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Clonality
Polyclonal
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Specificity
This item specifically recognises an epitope within the C-terminal (CT) region of the AD, ACD and ABCD isoforms of human BIM, otherwise known as Bcl-2 interacting mediator of cell death. BIM is an apoptotic activator protein and member of the Bcl-2 family, which forms heterodimers with several anti-apoptotic proteins including BCL2, BHRF1, and MCL1, but not with the pro-apoptotic proteins BAD, BAX or BAK. BIM can be induced by nerve growth factor (NGF) and also by forkhead transcription factor FKHR-L1, implicating BIM in both neuronal and lymphocyte apoptosis.
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Form
Purified Purified IgG - liquid
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Concentration
IgG concentration 0.5mg/ml
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Storage_stability
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
ELISA (EIA), Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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Latin name
Capra aegagrus hircus
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbol
BCL2L11
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Short name
GOAT ANTI BIM (C-TERMINAL)
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Technique
anti human, anti, Goat, antibody to, anti human antibodies, goats
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Host
Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
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Isotype
IgG
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Species
Human, Goats, Humans
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Alternative name
caprine antibody to H. sapiens BIM (C-TERMINAL)
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Alternative technique
antibodies, caprine
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Gene info
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Identity
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Gene
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Long gene name
BCL2 like 11
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Synonyms gene name
- BCL2-like 11 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year
1999-12-10
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Entrez gene record
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Pubmed identfication
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Classification
- BCL2 homology region 3 (BH3) only
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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