RABBIT ANTI AID (C-TERMINAL)

• Catalog number
  MBS223258
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [AID]
• Other_names
  [single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase]
• Products_gene_name
  [AID]
• Other_gene_names
  [AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID]
• Clonality
  Polyclonal
• Specificity
  This item recognises an epitope within the C-terminal region (CT) of Activation-induced cytidine deaminase (AID), a 24kDa homologue of the RNA-editing cytidine deaminase enzyme, APOBEC-1. Although the molecular mechanisms by which AID acts remain unclear, a growing number of studies reveal a requirement for AID during somatic hypermutation (SHM) and class switch recombination (CSR). These genetic modification events take place within highly specialised B cell germinal centres, during the final maturation stages of B cells, giving rise to high-affinity antibodies which use CSR to switch from IgM to IgG, IgA or IgE isotypes.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  AID  
• Gene symbol
  AICDA
• Short name
  RABBIT ANTI AID (C-TERMINAL)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Alternative name
  production species: rabbit antibody to AID (C-TERMINAL)
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:13203
• Gene
  AICDA
• Long gene name
  activation induced cytidine deaminase
• Synonyms gene name
  • activation-induced cytidine deaminase
• Synonyms
  • HIGM2
  • CDA2
  • ARP2
  • AID
• GenBank acession
  • AB040430
• Locus
  12p13.31
• Discovery year
  2000-09-19
• Entrez gene record
  57379
• Pubmed identfication
  • 29335468
• RefSeq identity
  • NM_020661
• Classification
  • Apolipoprotein B mRNA editing enzyme catalytic subunits
• VEGA ID
  OTTHUMG00000168676
• Locus Specific Databases
  • AICDA base: Mutation registry for Aid deficiency
  • LRG_17

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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