RAT ANTI HUMAN AID
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Catalog numberMBS219435
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PricePlease ask
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Size5x0.05 mg
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Products_typeAntibody
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Products_short_name[AID]
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Other_names[single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase]
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Products_gene_name[AID]
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Other_gene_names[AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID]
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ClonalityMonoclonal
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Clone[EK2-5G9]
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SpecificityThis item specifically recognizes human AID (Activation-induced cytidine deaminase), a 24kDa RNA-editing enzyme essential for the initiation of immunoglobulin class switch recombination (CSR), somatic hypermutation (SHM) and gene conversion (GC). Studies suggest that AID is selectively expressed by germinal centre (GC) B cells and B cell-derived lymphomas, and that a deficiency in AID is responsible for the autosomal recessive form of the immunodeficient condition Hyper-IgM syndrome.
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FormPurified Purified IgG - liquid
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ConcentrationIgG concentration 1.0 mg/ml
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Storage_stabilityStore at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_applicationELISA (EIA), Flow cytometry (FC/FACS)*, Immunohistology Paraffin*, Western Blot (WB)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameRattus norvegicus
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Gene target
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Gene symbolAICDA
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Short nameANTI AID
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Techniqueanti human, anti, antibody to, anti human antibodies
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HostRat
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IsotypeIgG2b
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SpeciesHuman, Humans, Rats
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Alternative nameRAT antibody to H. sapiens AID
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameactivation induced cytidine deaminase
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Synonyms gene name
- activation-induced cytidine deaminase
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-09-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Apolipoprotein B mRNA editing enzyme catalytic subunits
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data