PUMA alpha, epitope b (p53 Upregulated Modulator of Apoptosis)

• Catalog number
  MBS622331
• Price
  Please ask
• Size
  1 mg

• Products_type
  Antibody
• Products_short_name
  [PUMA alpha, epitope b]
• Products_name_syn
  [Anti -PUMA alpha, epitope b (p53 Upregulated Modulator of Apoptosis)]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human PUMA alpha
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The PUMA alpha, epitope b (p53 Upregulated Modulator of Apoptosis) is a α- or alpha protein sometimes glycoprotein present in blood. This 1 is suited for programmed cell-death studies.

• Gene target
  PUMA   alpha   epitope   p53   Upregulated   Modulator  
• Gene symbol
  BBC3, HCAR2
• Short name
  PUMA alpha, epitope b (p53 Upregulated Modulator of Apoptosis)
• Technique
  apoptosis, apoptosis pathway
• Host
  Rabbit
• Alternative name
  PUMA a, epitope b (p53 Upregulated Modulator on programmed cellular destruction)
• Alternative technique
  celldeath

Gene info

• Identity
  HGNC:17868
• Gene
  BBC3
• Long gene name
  BCL2 binding component 3
• Synonyms
  • JFY1
  • PUMA
• Synonyms name
  • p53-upregulated modulator of apoptosis
• GenBank acession
  • AF332558
• Locus
  19q13.32
• Discovery year
  2002-07-22
• Entrez gene record
  27113
• Pubmed identfication
  • 11463392
  • 11572983
• RefSeq identity
  • NM_014417
• Classification
  • BCL2 homology region 3 (BH3) only
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000183489

Gene info

• Identity
  HGNC:24827
• Gene
  HCAR2
• Long gene name
  hydroxycarboxylic acid receptor 2
• Synonyms gene
  • GPR109A
• Synonyms gene name
  • G protein-coupled receptor 109A
• Synonyms
  • HCA2
  • HM74A
  • PUMAG
  • Puma-g
  • NIACR1
• Synonyms name
  • niacin receptor 1
• GenBank acession
  • AY148884
• Locus
  12q24.31
• Discovery year
  2004-04-22
• Entrez gene record
  338442
• Pubmed identfication
  • 21167710
  • 12522134
  • 12646212
  • 19141678
  • 18983141
  • 21454438
• RefSeq identity
  • NM_177551
• Classification
  • Hydroxycarboxylic acid receptors
• VEGA ID
  OTTHUMG00000162722

MeSH Data

• Name
  Epitope Mapping
• Concept
  Scope note: Methods used for studying the interactions of antibodies with specific regions of protein antigens. Important applications of epitope mapping are found within the area of immunochemistry.
• Tree numbers
  • E05.478.274
  • E05.601.690.300
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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