PUMA (p53 Upregulated Modulator of Apoptosis, BCL2 Binding Component 3, BCL-2 Binding Component 3, BBC3, JFY1, JFY-1, p53 Up-regulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1)
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Catalog number
MBS621005
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Antibody
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Products_short_name
[PUMA]
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Products_name_syn
[Anti -PUMA (p53 Upregulated Modulator of Apoptosis, BCL2 Binding Component 3, BCL-2 Binding Component 3, BBC3, JFY1, JFY-1, p53 Up-regulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1)]
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Other_names
[PUMA; Bcl-2-binding component 3; bcl-2-binding component 3; p53 up-regulated modulator of apoptosis; Bcl-2 binding component 3; p53 up-regulated modulator of apoptosis]
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Other_gene_names
[Bbc3; Bbc3; Puma; Puma]
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Clonality
Polyclonal
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Reactivity
Human, Mouse, Rat
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Specificity
Recognizes human PUMA at ~23kD. A 16kD band may be seen in some instances. Species Crossreactivity: rat and mouse.
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Purity
Affinity Purified Purified by affinity chromatography.
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Form
Supplied as a liquid in PBS, 0.02% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
Western Blot (WB), Immunocytochemistry (ICC)
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Description
The PUMA (p53 Upregulated Modulator of Apoptosis, BCL2 Binding Component 3, BCL-2 Binding Component 3, BBC3, JFY1, JFY-1, p53 Up-regulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1) is a α- or alpha protein sometimes glycoprotein present in blood. This 1 is suited for programmed cell-death studies.
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Gene target
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Gene symbol
BBC3, BCL2, HCAR2, BCL2L1, BCL2L13, IGHVIII-2-1, BCL2L10, MIR1-2, TRUND-NNN9-1, BCL2L14
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Short name
PUMA (p53 Upregulated Modulator of Apoptosis, BCL2 Binding Component 3, BCL-2 Binding Component 3, BBC3, JFY1, JFY-1, p53 Up-regulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1)
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Technique
apoptosis, apoptosis pathway
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Host
Rabbit
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Isotype
IgG
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Alternative name
PUMA (p53 Upregulated Modulator on programmed cellular destruction, B-cellular CLL/lymphoma 2 Binding Component 3, BCL-2 Binding Component 3, B-cellular CLL/lymphoma 2 binding component 3, JFY1, JFY-1, p53 Up-regulated Modulator on programmed cellular destruction, PUMA a, PUMA/JFY1)
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Alternative technique
celldeath
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Alternative to gene target
B-cell CLL/lymphoma 2, Bcl-2 and PPP1R50, BCL2 and IDBG-4354 and ENSG00000171791 and 596, protein phosphatase 2A binding, nuclei, Bcl2 and IDBG-185673 and ENSMUSG00000057329 and 12043, BCL2 and IDBG-645006 and ENSBTAG00000019302 and 281020
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Gene info
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Identity
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Gene
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Long gene name
BCL2 binding component 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2002-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 homology region 3 (BH3) only
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
BCL2 apoptosis regulator
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Synonyms gene name
- B-cell CLL/lymphoma 2
- BCL2, apoptosis regulator
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- BCL2 family
- Protein phosphatase 1 regulatory subunits
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VEGA ID
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Locus Specific Databases
Gene info
Gene info
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Identity
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Gene
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Long gene name
BCL2 like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-10-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
BCL2 like 13
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Synonyms gene name
- BCL2-like 13 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2002-09-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
BCL2 like 10
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Synonyms gene name
- BCL2-like 10 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year
1999-05-21
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
microRNA 1-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
Gene info
Gene info
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Identity
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Gene
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Long gene name
BCL2 like 14
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Synonyms gene name
- BCL2-like 14 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2004-02-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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