Proteinase-activated Receptor 1 (PAR-1, Coagulation Factor II Receptor, Thrombin Receptor, F2R, CF2R, PAR1, TR)

• Catalog number
  MBS630211
• Price
  Please ask
• Size
  0,05 mg

• Other size
  please contact us to order other different size
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Proteinase-activated   Receptor   PAR-1   Coagulation   Factor   Receptor   Thrombin   Receptor   F2R   CF2R   PAR1  
• Gene symbol
  F2R, PWAR1, SLC52A2, MARK2, PARD6B, PARD6G, PARD6A, JTB, PWAR4, PWAR5
• Short name
  Proteinase-activated Receptor 1 (PAR-1, Coagulation Factor II Receptor, Thrombin Receptor, F2R, CF2R, PAR1, TR)
• Alternative name
  Proteinase-activated Receptor 1 (PAR-1, Coagulation Factor II Receptor, Thrombin Receptor, coagulation factor II (thrombin) receptor, CF2R, PAR1, TR)
• Alternative to gene target
  coagulation factor II (thrombin) receptor, CF2R and HTR and PAR-1 and PAR1 and TR, F2R and IDBG-29671 and ENSG00000181104 and 2149, G-protein beta-subunit binding, Extracellular, F2r and IDBG-174004 and ENSMUSG00000048376 and 14062, BT.69975 and IDBG-645158 and ENSBTAG00000020199 and 526585

Gene info

• Identity
  HGNC:3537
• Gene
  F2R
• Long gene name
  coagulation factor II thrombin receptor
• Synonyms gene name
  • coagulation factor II (thrombin) receptor
• Synonyms
  • TR
  • CF2R
  • PAR1
  • PAR-1
• Synonyms name
  • protease activated receptor 1
• GenBank acession
  • M62424
• Locus
  5q13.3
• Discovery year
  1991-07-16
• Entrez gene record
  2149
• Pubmed identfication
  • 8395910
• RefSeq identity
  • NM_001992
• Classification
  • F2R receptors
• VEGA ID
  OTTHUMG00000131299
• Locus Specific Databases
  • LRG_641

Gene info

• Identity
  HGNC:30089
• Gene
  PWAR1
• Long gene name
  Prader Willi/Angelman region RNA 1
• Synonyms
  • PAR1
  • PAR-1
• Synonyms name
  • Prader Willi/Angelman region 1
• Locus
  15q11.2
• Discovery year
  2013-06-14
• Entrez gene record
  145624
• Pubmed identfication
  • 7987392
  • 9477342
• RefSeq identity
  • NR_022009
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000176879

Gene info

• Identity
  HGNC:30224
• Gene
  SLC52A2
• Long gene name
  solute carrier family 52 member 2
• Synonyms gene
  • GPR172A
• Synonyms gene name
  • G protein-coupled receptor 172A
  • solute carrier family 52 (riboflavin transporter), member 2
• Synonyms
  • FLJ11856
  • PAR1
  • GPCR41
  • D15Ertd747e
  • RFVT2
  • hRFT3
• GenBank acession
  • AY070774
• Locus
  8q24.3
• Discovery year
  2004-07-19
• Entrez gene record
  79581
• Pubmed identfication
  • 12740431
• RefSeq identity
  • NM_024531
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000165168

Gene info

• Identity
  HGNC:3332
• Gene
  MARK2
• Long gene name
  microtubule affinity regulating kinase 2
• Synonyms gene
  • EMK1
• Synonyms gene name
  • ELKL motif kinase
  • MAP/microtubule affinity-regulating kinase 2
• Synonyms
  • PAR-1
  • Par1b
  • PAR-1B
• Synonyms name
  • ELKL motif kinase 1
  • serine/threonine kinase
  • protein-serine/threonine kinase
  • Ser/Thr protein kinase PAR-1B
• GenBank acession
  • BC008771
• Locus
  11q13.1
• Discovery year
  1994-12-08
• Entrez gene record
  2011
• Pubmed identfication
  • 9730619
  • 10516437
• RefSeq identity
  • NM_017490
• VEGA ID
  OTTHUMG00000160504

Gene info

• Identity
  HGNC:16245
• Gene
  PARD6B
• Long gene name
  par-6 family cell polarity regulator beta
• Synonyms gene name
  • par-6 (partitioning defective 6, C.elegans) homolog beta
  • par-6 partitioning defective 6 homolog beta (C. elegans)
• Synonyms
  • PAR-6B
• GenBank acession
  • AB044555
• Locus
  20q13.13
• Discovery year
  2001-08-01
• Entrez gene record
  84612
• Pubmed identfication
  • 11260256
• RefSeq identity
  • NM_032521
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000032732

Gene info

• Identity
  HGNC:16076
• Gene
  PARD6G
• Long gene name
  par-6 family cell polarity regulator gamma
• Synonyms gene name
  • par-6 (partitioning defective 6, C.elegans) homolog gamma
  • par-6 partitioning defective 6 homolog gamma (C. elegans)
• Synonyms
  • PAR-6G
  • PAR6gamma
• Locus
  18q23
• Discovery year
  2001-07-31
• Entrez gene record
  84552
• Pubmed identfication
  • 11260256
• RefSeq identity
  • NM_032510
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000132922

Gene info

• Identity
  HGNC:15943
• Gene
  PARD6A
• Long gene name
  par-6 family cell polarity regulator alpha
• Synonyms gene name
  • par-6 (partitioning defective 6, C.elegans) homolog alpha
  • par-6 partitioning defective 6 homolog alpha (C. elegans)
• Synonyms
  • PAR-6
  • PAR-6A
  • TAX40
  • PAR6alpha
  • TIP-40
• Locus
  16q22.1
• Discovery year
  2001-06-21
• Entrez gene record
  50855
• Pubmed identfication
  • 9482110
  • 11260256
• RefSeq identity
  • NM_016948
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000137534

Gene info

• Identity
  HGNC:6201
• Gene
  JTB
• Long gene name
  jumping translocation breakpoint
• Synonyms
  • hJT
  • PAR
• Synonyms name
  • prostate androgen-regulated gene
• GenBank acession
  • AB016488
• Locus
  1q21.3
• Discovery year
  2000-01-31
• Entrez gene record
  10899
• Pubmed identfication
  • 10321732
  • 27751357
  • 22079049
• RefSeq identity
  • NM_006694
• VEGA ID
  OTTHUMG00000036590

Gene info

• Identity
  HGNC:29998
• Gene
  PWAR4
• Long gene name
  Prader Willi/Angelman region RNA 4
• Synonyms
  • PAR4
  • PAR-4
• Locus
  15q11.2
• Discovery year
  2013-06-14
• Entrez gene record
  347745
• Pubmed identfication
  • 11106375
  • 7987392
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:30090
• Gene
  PWAR5
• Long gene name
  Prader Willi/Angelman region RNA 5
• Synonyms
  • PAR5
  • PAR-5
• Synonyms name
  • Prader Willi/Angelman syndrome 5
• Locus
  15q11.2
• Discovery year
  2013-06-14
• Entrez gene record
  8123
• Pubmed identfication
  • 7987392
  • 9477342
  • 23726844
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000184194

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