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Products_type
Antibody
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Products_short_name
[F2R / Thrombin Receptor / PAR1]
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Products_name_syn
[Anti-F2R / Thrombin Receptor / PAR1 Antibody IHC-plus; F2R; CF2R; Coagulation factor II receptor; PAR1; PAR-1; Thrombin receptor; TR; HTR; Protease-activated receptor 1; Human F2R; Thrombin Receptor; PAR1]
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Other_names
[proteinase-activated receptor 1; Proteinase-activated receptor 1; proteinase-activated receptor 1; protease-activated receptor 1; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; Thrombin receptor]
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Products_gene_name
[F2R]
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Other_gene_names
[F2R; F2R; TR; HTR; CF2R; PAR1; PAR-1; CF2R; PAR1; TR; PAR-1]
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Clonality
Polyclonal
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Reactivity
Gorilla, Human Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity)
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Specificity
Human F2R / Thrombin receptor.
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Purity
Immunoaffinity Purified
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Form
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
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Concentration
0.5 mg/ml
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Storage_stability
Store at -20 degree C. Minimize freezing and thawing.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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Latin name
Capra aegagrus hircus
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
F2R, PWAR1, SLC52A2
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Short name
Goat Polyclonal F2R / Thrombin Receptor / PAR1
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Technique
Polyclonal, Goat, goats, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
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Species
Human, Goats, Humans
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Alternative name
caprine polyclonal to H. sapiens coagulation factor II (thrombin) receptor / Thrombin Receptor / PAR1
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Alternative technique
polyclonals, caprine
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Alternative to gene target
coagulation factor II (thrombin) receptor, CF2R and HTR and PAR-1 and PAR1 and TR, F2R and IDBG-29671 and ENSG00000181104 and 2149, G-protein beta-subunit binding, Extracellular, F2r and IDBG-174004 and ENSMUSG00000048376 and 14062, BT.69975 and IDBG-645158 and ENSBTAG00000020199 and 526585
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