PRAME (Melanoma Antigen Preferentially Expressed in Tumors, Opa-interacting Protein 4, OIP-4, Preferentially Expressed Antigen of Melanoma, MAPE, OIP4)

• Catalog number
  MBS645405
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [PRAME]
• Products_name_syn
  [Anti -PRAME (Melanoma Antigen Preferentially Expressed in Tumors, Opa-interacting Protein 4, OIP-4, Preferentially Expressed Antigen of Melanoma, MAPE, OIP4)]
• Other_names
  [PRAME; Melanoma antigen preferentially expressed in tumors; Opa-interacting protein 4; OIP-4; Preferentially expressed antigen of melanoma]
• Other_gene_names
  [PRAME; MAPE; OIP4; OIP-4]
• Clonality
  Polyclonal
• Reactivity
  Canine, Human, Monkey
• Specificity
  Recognizes human PRAME. Species Crossreactivity
• Purity
  Serum Serum.
• Form
  Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Western Blot (WB)
• Description
  Antigens are peptides or recombinant or native dependent on the production method.

• Gene target
  PRAME   Melanoma   Preferentially   Expressed   Tumors   Opa-interacting   Protein   OIP-4   Preferentially   Expressed   Melanoma   MAPE   OIP4  
• Gene symbol
  PRAME, MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4, IGKV2OR2-4, ANKRD20A12P
• Short name
  PRAME (Melanoma Antigen Preferentially Expressed in Tumors, Opa-interacting Protein 4, OIP-4, Preferentially Expressed Antigen of Melanoma, MAPE, OIP4)
• Technique
  antigen, antigenes
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  preferentially expressed antigen in melanoma (Melanoma protein Preferentially Expressed in Tumors, Opa-interacting Protein 4, OIP-4, Preferentially Expressed protein on Melanoma, MAPE, OIP4)
• Alternative technique
  antigenes
• Alternative to gene target
  preferentially expressed antigen in melanoma, CT130 and MAPE and OIP-4 and OIP4, PRAME and IDBG-2240 and ENSG00000185686 and 23532, retinoic acid receptor binding, nuclei

Gene info

• Identity
  HGNC:9336
• Gene
  PRAME
• Long gene name
  PRAME nuclear receptor transcriptional regulator
• Synonyms gene
  • MAPE
• Synonyms gene name
  • preferentially expressed antigen in melanoma
• Synonyms
  • CT130
• Synonyms name
  • cancer/testis antigen 130
• GenBank acession
  • U65011
• Locus
  22q11.22
• Discovery year
  1996-06-21
• Entrez gene record
  23532
• Pubmed identfication
  • 9047241
  • 10591208
• RefSeq identity
  • NM_206953
• Classification
  • PRAME family
• VEGA ID
  OTTHUMG00000151172

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

Gene info

• Identity
  HGNC:43603
• Gene
  ANKRD20A12P
• Long gene name
  ankyrin repeat domain 20 family member A12, pseudogene
• Synonyms gene name
  • ankyrin repeat domain 20 family, member A12, pseudogene
• Locus
  4
• Discovery year
  2011-11-23
• Entrez gene record
  100874392

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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