Human Melanoma antigen preferentially expressed in tumors (PRAME)

Description

Recombinant Human Melanoma antigen preferentially expressed in tumors(PRAME) expressed in Yeast
Specifications

Uniprot ID: P78395; Host: Homo sapiens (Human); Expression system: Yeast; Expression region: 1-509aa; Sequence information: Full Length; Tag: N-terminal 6xHis-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
Additional_information

MW: 59.9 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
Storage_and_shipping

Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
Notes

For research use only.
Additional description

Antigens are peptides or recombinant or native dependent on the production method.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

Melanoma preferentially expressed tumors PRAME
Gene symbol

PRAME
Short name

Melanoma antigen preferentially expressed in tumors (PRAME)
Technique

antigen, antigenes
Species

Human, Humans
Alternative name

H. sapiens Melanoma protein preferentially expressed in tumors (preferentially expressed antigen in melanoma)
Alternative technique

antigenes
Alternative to gene target

preferentially expressed antigen in melanoma, CT130 and MAPE and OIP-4 and OIP4, PRAME and IDBG-2240 and ENSG00000185686 and 23532, retinoic acid receptor binding, nuclei

Name

Tumor Stem Cell Assay
Concept

Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data