Platelet Glycoprotein IIb-IIIa

Products_type

Antibody
Products_short_name

[Platelet Glycoprotein IIb-IIIa]
Products_name_syn

[Anti -Platelet Glycoprotein IIb-IIIa]
Other_names

[platelet glycoprotein IIb; integrin alpha-IIb; integrin alpha 2b; platelet glycoprotein IIb]
Other_gene_names

[ITGA2B]
Clonality

Polyclonal
Reactivity

Human
Specificity

Monospecific for GPIIb-IIIa when analysed by immunoelectrophoresis and ELISA.
Purity

Purified Purified by caprylic acid and ammonium sulfate precipitations, and solid -phase adsorption to remove unwanted crossreactivity.
Form

Supplied in a solution of 10mM HEPES, pH7.4, 0.15M sodium chloride and 50% glycerol. No preservative is added.
Storage_stability

May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

ELISA (EL/EIA)
Description

Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures.

Identity

HGNC:6138
Gene

ITGA2B
Long gene name

integrin subunit alpha 2b
Synonyms gene
- GP2B
Synonyms gene name
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Synonyms
- CD41B
- CD41
- PPP1R93
Synonyms name
- protein phosphatase 1, regulatory subunit 93
- platelet glycoprotein IIb of IIb/IIIa complex
Locus

17q21.31
Discovery year

1986-01-01
Entrez gene record

3674
Classification
- CD molecules
- Integrin alpha subunits
- Protein phosphatase 1 regulatory subunits
VEGA ID

OTTHUMG00000177935
Locus Specific Databases
- LRG_479