Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa)

  • Catalog number
    RPU52596
  • Price
    Please ask
  • Size
    10 μg
  • Verified reactivity
    Homo sapiens (Human)
  • Protein number
    P16234
  • Gene name
    Please refer to GenBank
  • Other name
    CD140a; PDGFR2; Rhe-PDGFRA; CD140 antigen-like family member A; Platelet-derived growth factor receptor 2; Alpha-type platelet-derived growth factor receptor
  • Protein origin
    E.coli
  • Protein region
    Please contact us.
  • Protein sequence
    Please contact us.
  • Information about sequence
    Ala170~Glu387
  • Expected molecular weight
    28,6kDa
  • Protein purity
    ≥ 95%
  • Verified applications
    SDS-PAGE; WB; ELISA; IP.
  • Storage recommendation
    Aliquot and store at -20°C. Minimize freezing and thawing.
  • Use before
    1 year
  • Shipping requirements
    Blue ice
  • Estimated production time
    7-11 business days
  • Notes
    For research use only. Not for diagnostic procedures.
  • Description
    The Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    PDGFRA
  • Short name
    Recombinant Platelet Derived Growth Factor Receptor Alpha (PDGFRa)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Label
    two N-terminal Tags, His-tag and T7-tag
  • Alternative name
    Rec. Platelet Derived Growth Factor Receptor a (platelet-derived growth factor receptor, a polypeptide)
  • Alternative technique
    rec
  • Alternative to gene target
    platelet-derived growth factor receptor, alpha polypeptide, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, transferase activity, nuclei, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301
Gene info
  • Identity
  • Gene
  • Long gene name
    platelet derived growth factor receptor alpha
  • Synonyms gene name
    • platelet-derived growth factor receptor, alpha polypeptide
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1989-05-19
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • I-set domain containing
    • Receptor tyrosine kinases
    • CD molecules
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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