Plasminogen Activator Inhibitor Type 1 P14 Arg, stable mutant, Human (PAI-1)
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Catalog numberMBS634604
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PricePlease ask
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Size0,5 mg
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Other sizeplease contact us to order other different size
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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GenePlasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis
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Gene target
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Gene symbolSERPINE1, RPL34P24, RPP14, H3P8, SUB1, CDK2AP2
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Short namePlasminogen Activator Inhibitor 1 P14 Arg, stable mutant, (PAI-1)
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SpeciesHuman, Humans
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Alternative namePlasminogen Activator suppressor classification 1 P14 L-arginine, stable mutant, H. sapiens (PAI-1)
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Gene info
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Identity
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Gene
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Long gene nameserpin family E member 1
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Synonyms gene
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Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serpin peptidase inhibitors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameribosomal protein L34 pseudogene 24
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Locus
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Discovery year2009-03-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameribonuclease P/MRP subunit p14
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Synonyms gene name
- ribonuclease P 14kDa subunit
- ribonuclease P/MRP 14kDa subunit
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-03-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 histone pseudogene 8
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Synonyms
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Locus
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Discovery year2019-08-02
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameSUB1 regulator of transcription
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Synonyms gene name
- SUB1 homolog (S. cerevisiae)
- SUB1 homolog, transcriptional regulator
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-08-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecyclin dependent kinase 2 associated protein 2
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Synonyms gene name
- CDK2-associated protein 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-04-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID