Human Plasminogen activator inhibitor 1 (SERPINE1)

• Catalog number
  CSB-RP112394h-10ug
• Price
  Please ask
• Size
  10ug

• Description
  Recombinant Human Plasminogen activator inhibitor 1(SERPINE1),partial expressed in E.coli
• Specifications
  Uniprot ID: P05121; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 24-401aa; Sequence information: Partial; Tag: N-terminal 6xHis-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
• Additional_information
  MW: 46.7 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
• Storage_and_shipping
  Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
• Notes
  For research use only.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Plasminogen   activator   inhibitor   SERPINE1  
• Gene symbol
  SERPINE1
• Short name
  Plasminogen activator inhibitor 1 (SERPINE1)
• Species
  Human, Humans
• Alternative name
  H. sapiens Plasminogen activator suppressor 1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor classification 1), member 1)
• Alternative to gene target
  serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, PAI and PAI-1 and PAI1 and PLANH1, SERPINE1 and IDBG-32959 and ENSG00000106366 and 5054, protein binding, Extracellular, Serpine1 and IDBG-204786 and ENSMUSG00000037411 and 18787, SERPINE1 and IDBG-640415 and ENSBTAG00000014465 and 281375

Gene info

• Identity
  HGNC:8583
• Gene
  SERPINE1
• Long gene name
  serpin family E member 1
• Synonyms gene
  • PLANH1
  • PAI1
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
• Synonyms
  • PAI
• Synonyms name
  • plasminogen activator inhibitor, type I
• GenBank acession
  • M16006
• Locus
  7q22.1
• Discovery year
  1986-01-01
• Entrez gene record
  5054
• Pubmed identfication
  • 3097076
  • 2891140
  • 24172014
• RefSeq identity
  • NM_000602
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000157107
• Locus Specific Databases
  • LRG_597

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