Plasminogen Activator Inhibitor 1 (PAI-1) (Western Blot Control)

Other size

please contact us to order other different size
Test

Western Blot can be performed on tissues and cell extracts to determine the proteins present in your sample after PAGE electrophoresis and transfer on PVDF or Nitrocellulose. PVDF is more advised. The best detection method is using enhanced chemiluminescence or ECL.
Description

Isotype or positive controls by peptides, antibodies and deactivated samples. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Gene

Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis

Gene target

Plasminogen Activator Inhibitor PAI-1
Gene symbol

SERPINE1, SERPINB2, SERBP1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
Short name

Plasminogen Activator Inhibitor 1 (PAI-1) ( Blot Control)
Technique

Western Blot, Control, Blot, western Blots, controls
Alternative name

Plasminogen Activator suppressor 1 (PAI-1) (Western Blot reference)
Alternative technique

controls, western
Tissue

control

Identity

HGNC:8583
Gene

SERPINE1
Long gene name

serpin family E member 1
Synonyms gene
- PLANH1
- PAI1
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Synonyms
- PAI
Synonyms name
- plasminogen activator inhibitor, type I
GenBank acession
- M16006
Locus

7q22.1
Discovery year

1986-01-01
Entrez gene record

5054
Pubmed identfication
- 3097076
- 2891140
- 24172014
RefSeq identity
- NM_000602
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000157107
Locus Specific Databases
- LRG_597

Identity

HGNC:8584
Gene

SERPINB2
Long gene name

serpin family B member 2
Synonyms gene
- PLANH2
- PAI2
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
- serpin peptidase inhibitor, clade B (ovalbumin), member 2
Synonyms
- HsT1201
- PAI-2
Synonyms name
- plasminogen-activator inhibitor
GenBank acession
- Y00630
Locus

18q21.33-q22.1
Discovery year

1989-02-07
Entrez gene record

5055
Pubmed identfication
- 24172014
RefSeq identity
- NM_002575
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000060592

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data