Pegylated mouse super leptin antagonist (mutant D23/L39A/D40A/F41A)
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Catalog number
MBS400080
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Price
Please ask
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Size
10 mg
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Products_type
Active Protein
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Products_short_name
[Pegylated super leptin antagonist]
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Products_name_syn
[Mouse pegylated super leptin antagonist (mutant D23L/L39A/D40A/F41A)]
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Purity
The purity of pegylated recombinant super mouse leptin antagonist is greater than 95.0% as determined by:(a) Gel filtration analysis.(b) Analysis by reducing and non-reducing SDS-PAGE gel.
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Form
The pegylated recombinant super mouse leptin antagonist was lyophilized from a concentrated (0.65mg/ml) solution with 0.003mM NaHCO3.
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Storage_stability
Lyophilized pegylated recombinant super mouse leptin antagonistal though stable at room temperature for several weeks, should be stored desiccated below - 20 degree C. Upon reconstitution of pegylated recombinant super mouse leptin antagonist at > 0.1 mg/ml and up to 2 mg/ml and filter sterilization pegylated recombinant super mouse leptin antagonist mutant can be stored at 4 degree C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.
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Description
The antagonist receptor ligand binding will be in contrast with agonist activity. MyBioSource produces more antagonist and receptor related products as 1.
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Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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