Pegylated human super leptin antagonist (mutant D23/L39A/D40A/F41A)
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Catalog number
MBS400077
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Price
Please ask
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Size
0.05 mg
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Products_type
Active Protein
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Products_short_name
[Pegylated super leptin antagonist]
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Products_name_syn
[Human pegylated super leptin antagonist (mutant D23L/L39A/D40A/F41A)]
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Purity
The purity of human pegylated leptin antagonist is greater than 98.0% as determined by:(a) Gel filtration analysis.(b) Analysis by reducing and non-reducing SDS-PAGE gel.
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Form
White lyophilized (freeze-dried) powder.
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Storage_stability
Lyophilized human pegylated leptin antagonist although stable at room temperature for several weeks, should be stored desiccated below - 20 degree C. Upon reconstitution at > 0.1 mg/ml and up to 2 mg/ml of human pegylated leptin antagonist and filter sterilization human pegylated leptin antagonist can be stored at 4 degree C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.
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Description
The antagonist receptor ligand binding will be in contrast with agonist activity. MyBioSource produces more antagonist and receptor related products as 1.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
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