PAR-2 (Proteinase-activated receptor 2, F2RL1, Coagulation Factor II (thrombin) receptor-like 1, Coagulation Factor II receptor-like 1, GPR11, G-protein coupled receptor 11, PAR2, Thrombin receptor-like 1)

• Catalog number
  MBS601311
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [PAR-2]
• Products_name_syn
  [Anti -PAR-2 (Proteinase-activated receptor 2, F2RL1, Coagulation Factor II (thrombin) receptor-like 1, Coagulation Factor II receptor-like 1, GPR11, G-protein coupled receptor 11, PAR2, Thrombin receptor-like 1)]
• Other_names
  [proteinase-activated receptor 2; Proteinase-activated receptor 2; proteinase-activated receptor 2; PAR-2; OTTHUMP00000128315; thrombin receptor-like 1; G protein-coupled receptor-11; G-protein coupled receptor 11; protease-activated receptor 2; proteinase-activated receptor-2; coagulation factor II receptor-like 1; coagulation factor II (thrombin) receptor-like 1; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1]
• Other_gene_names
  [F2RL1; F2RL1; PAR2; GPR11; GPR11; PAR2]
• Clonality
  Monoclonal
• Clone
  [3G233]
• Reactivity
  Human
• Specificity
  Recognizes native peptide and the N-terminus of the human PAR-2. Does not crossreact with PAR-1.
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  PAR-2   Proteinase-activated   receptor   F2RL1   Coagulation   Factor   thrombin   receptor-like   Coagulation   Factor   receptor-like   GPR11   G-protein   coupled   receptor   PAR2   Thrombin   receptor-like  
• Gene symbol
  F2RL1, NR1I2, SLC52A1, PARD6B, PARD6G, MARK2, PARD6A, JTB, PWAR1, PWAR4
• Short name
  PAR-2 (Proteinase-activated receptor 2, F2RL1, Coagulation Factor II (thrombin) receptor-like 1, Coagulation Factor II receptor-like 1, GPR11, G-protein coupled receptor 11, PAR2, Thrombin receptor-like 1)
• Host
  Mouse
• Isotype
  IgG2a
• Alternative name
  PAR-2 (Proteinase-activated receptor 2, coagulation factor II (thrombin) receptor-like 1, Coagulation Factor II (thrombin) receptor-like 1, Coagulation Factor II receptor-like 1, GPR11, G-protein coupled receptor 11, PAR2, Thrombin receptor-like 1)
• Alternative to gene target
  coagulation factor II (thrombin) receptor-like 1, GPR11 and PAR2, F2RL1 and IDBG-29713 and ENSG00000164251 and 2150, G-protein beta-subunit binding, Plasma membranes, F2rl1 and IDBG-173973 and ENSMUSG00000021678 and 14063, BT.28745 and IDBG-645161 and ENSBTAG00000034848 and 526525

Gene info

• Identity
  HGNC:3538
• Gene
  F2RL1
• Long gene name
  F2R like trypsin receptor 1
• Synonyms gene
  • GPR11
• Synonyms gene name
  • coagulation factor II (thrombin) receptor-like 1
• Synonyms
  • PAR2
• Synonyms name
  • proteinase-activated receptor-2
• GenBank acession
  • BC018130
• Locus
  5q13.3
• Discovery year
  1997-10-27
• Entrez gene record
  2150
• Pubmed identfication
  • 7937743
  • 7556175
• RefSeq identity
  • NM_005242
• Classification
  • F2R receptors
• VEGA ID
  OTTHUMG00000102118

Gene info

• Identity
  HGNC:7968
• Gene
  NR1I2
• Long gene name
  nuclear receptor subfamily 1 group I member 2
• Synonyms gene name
  • nuclear receptor subfamily 1, group I, member 2
• Synonyms
  • ONR1
  • PXR
  • BXR
  • SXR
  • PAR2
• Synonyms name
  • pregnane X receptor
  • orphan nuclear receptor PXR
• GenBank acession
  • AF061056
• Locus
  3q13.33
• Discovery year
  1999-04-23
• Entrez gene record
  8856
• Pubmed identfication
  • 9727070
  • 9770465
• Classification
  • Nuclear receptor subfamily 1 group I
• VEGA ID
  OTTHUMG00000159400

Gene info

• Identity
  HGNC:30225
• Gene
  SLC52A1
• Long gene name
  solute carrier family 52 member 1
• Synonyms gene
  • GPR172B
• Synonyms gene name
  • G protein-coupled receptor 172B
  • solute carrier family 52 (riboflavin transporter), member 1
• Synonyms
  • FLJ10060
  • GPCR42
  • PAR2
  • hRFT1
  • RFVT1
• Synonyms name
  • riboflavin transporter 1
• GenBank acession
  • AY070775
• Locus
  17p13.2
• Discovery year
  2004-07-19
• Entrez gene record
  55065
• Pubmed identfication
  • 12740431
  • 18632736
• RefSeq identity
  • NM_017986
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000099448

Gene info

• Identity
  HGNC:16245
• Gene
  PARD6B
• Long gene name
  par-6 family cell polarity regulator beta
• Synonyms gene name
  • par-6 (partitioning defective 6, C.elegans) homolog beta
  • par-6 partitioning defective 6 homolog beta (C. elegans)
• Synonyms
  • PAR-6B
• GenBank acession
  • AB044555
• Locus
  20q13.13
• Discovery year
  2001-08-01
• Entrez gene record
  84612
• Pubmed identfication
  • 11260256
• RefSeq identity
  • NM_032521
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000032732

Gene info

• Identity
  HGNC:16076
• Gene
  PARD6G
• Long gene name
  par-6 family cell polarity regulator gamma
• Synonyms gene name
  • par-6 (partitioning defective 6, C.elegans) homolog gamma
  • par-6 partitioning defective 6 homolog gamma (C. elegans)
• Synonyms
  • PAR-6G
  • PAR6gamma
• Locus
  18q23
• Discovery year
  2001-07-31
• Entrez gene record
  84552
• Pubmed identfication
  • 11260256
• RefSeq identity
  • NM_032510
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000132922

Gene info

• Identity
  HGNC:3332
• Gene
  MARK2
• Long gene name
  microtubule affinity regulating kinase 2
• Synonyms gene
  • EMK1
• Synonyms gene name
  • ELKL motif kinase
  • MAP/microtubule affinity-regulating kinase 2
• Synonyms
  • PAR-1
  • Par1b
  • PAR-1B
• Synonyms name
  • ELKL motif kinase 1
  • serine/threonine kinase
  • protein-serine/threonine kinase
  • Ser/Thr protein kinase PAR-1B
• GenBank acession
  • BC008771
• Locus
  11q13.1
• Discovery year
  1994-12-08
• Entrez gene record
  2011
• Pubmed identfication
  • 9730619
  • 10516437
• RefSeq identity
  • NM_017490
• VEGA ID
  OTTHUMG00000160504

Gene info

• Identity
  HGNC:15943
• Gene
  PARD6A
• Long gene name
  par-6 family cell polarity regulator alpha
• Synonyms gene name
  • par-6 (partitioning defective 6, C.elegans) homolog alpha
  • par-6 partitioning defective 6 homolog alpha (C. elegans)
• Synonyms
  • PAR-6
  • PAR-6A
  • TAX40
  • PAR6alpha
  • TIP-40
• Locus
  16q22.1
• Discovery year
  2001-06-21
• Entrez gene record
  50855
• Pubmed identfication
  • 9482110
  • 11260256
• RefSeq identity
  • NM_016948
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000137534

Gene info

• Identity
  HGNC:6201
• Gene
  JTB
• Long gene name
  jumping translocation breakpoint
• Synonyms
  • hJT
  • PAR
• Synonyms name
  • prostate androgen-regulated gene
• GenBank acession
  • AB016488
• Locus
  1q21.3
• Discovery year
  2000-01-31
• Entrez gene record
  10899
• Pubmed identfication
  • 10321732
  • 27751357
  • 22079049
• RefSeq identity
  • NM_006694
• VEGA ID
  OTTHUMG00000036590

Gene info

• Identity
  HGNC:30089
• Gene
  PWAR1
• Long gene name
  Prader Willi/Angelman region RNA 1
• Synonyms
  • PAR1
  • PAR-1
• Synonyms name
  • Prader Willi/Angelman region 1
• Locus
  15q11.2
• Discovery year
  2013-06-14
• Entrez gene record
  145624
• Pubmed identfication
  • 7987392
  • 9477342
• RefSeq identity
  • NR_022009
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000176879

Gene info

• Identity
  HGNC:29998
• Gene
  PWAR4
• Long gene name
  Prader Willi/Angelman region RNA 4
• Synonyms
  • PAR4
  • PAR-4
• Locus
  15q11.2
• Discovery year
  2013-06-14
• Entrez gene record
  347745
• Pubmed identfication
  • 11106375
  • 7987392
• Classification
  • Long non-coding RNAs with non-systematic symbols

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