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Products_type
Antibody
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Products_short_name
[NRG1]
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Products_name_syn
[Anti -NRG1, ID (NRG1, GGF, HGL, HRGA, NDF, SMDF, Pro-neuregulin-1, membrane-bound isoform, Neuregulin-1, Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, Neu differentiation factor, Sensory]
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Other_names
[NRG1; Pro-neuregulin-1, membrane-bound isoform; pro-neuregulin-1, membrane-bound isoform; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator); neuregulin 1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-derived factor]
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Other_gene_names
[NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Human
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Purity
Affinity Purified Purified by Protein G affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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Description
For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
NRG1, NRG1-IT1, NRG1-IT3, LIPF, LLGL2
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Short name
NRG1, ID (NRG1, GGF, HGL, HRGA, NDF, SMDF, Pro-neuregulin-1, -bound isoform, Neuregulin-1, Acetylcholine receptor- activity, Breast cancer differentiation factor p45, Glial growth factor, Heregulin, Neu differentiation factor, Sensory
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Host
Rabbit
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Isotype
IgG
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Alternative name
neuregulin 1, ID (neuregulin 1, GGF, HGL, HRGA, NDF, SMDF, L-proline-neuregulin-1, membrane-bound isoform, Neuregulin-1, Acetylcholine receptor-inducing activity, Breast cancer cellular differentiation factor p45, Glial growth factor, Heregulin, Neu differentiation factor, Sensory
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Alternative to gene target
neuregulin 1, ARIA and GGF and GGF2 and HGL and HRG and HRG1 and HRGA and MST131 and MSTP131 and NDF and NRG1-IT2 and SMDF, NRG1 and IDBG-16182 and ENSG00000157168 and 3084, ErbB-3 class receptor binding, nuclei, Nrg1 and IDBG-146861 and ENSMUSG00000062991 and 211323, NRG1 and IDBG-628923 and ENSBTAG00000004150 and 281361
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Tissue
breast, cell
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Disease
cancer
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