Nephrin, phosphorylated (Tyr1176/Tyr1193) (NPHN, CNF, Nephrosis 1 Congenital Finnish Type, NPHS1, Renal Glomerulus-specific Cell Adhesion Receptor)[Nephrin]

• Catalog number
  MBS632703
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Nephrin, phosphorylated (Tyr1176/Tyr1193) (NPHN, CNF, Nephrosis 1 Congenital Finnish , NPHS1, Renal Glomerulus-specific Adhesion Receptor)[Nephrin]. For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Nephrin   phosphorylated   Tyr1176/Tyr1193   NPHN   CNF   Nephrosis   Congenital   Finnish   NPHS1   Renal   Glomerulus-specific   Adhesion   Receptor   [Nephrin]  
• Gene symbol
  NPHS1
• Short name
  Nephrin, phosphorylated (Tyr1176/Tyr1193) (NPHN, CNF, Nephrosis 1 Congenital Finnish , NPHS1, Renal Glomerulus-specific Adhesion Receptor)[Nephrin]
• Host
  Rabbit
• Alternative name
  Nephrin, phosphorylated (Tyr1176/Tyr1193) (NPHN, CNF, Nephrosis 1 Congenital Finnish classification, nephrosis 1, congenital, Finnish classification (nephrin), Renal Glomerulus-specific cellular Adhesion Receptor)[Nephrin]
• Alternative to gene target
  nephrosis 1, congenital, Finnish type (nephrin), CNF and nephrin and NPHN, NPHS1 and IDBG-45496 and ENSG00000161270 and 4868, alpha-actinin binding, Plasma membranes, Nphs1 and IDBG-169263 and ENSMUSG00000006649 and 54631, NPHS1 and IDBG-636002 and ENSBTAG00000007821 and 519706
• Tissue
  cell
• Disease
  congenital

Gene info

• Identity
  HGNC:7908
• Gene
  NPHS1
• Long gene name
  NPHS1 adhesion molecule, nephrin
• Synonyms gene name
  • nephrosis 1, congenital, Finnish type (nephrin)
  • NPHS1, nephrin
• Synonyms
  • CNF
  • NPHN
• Locus
  19q13.12
• Discovery year
  1994-12-14
• Entrez gene record
  4868
• Pubmed identfication
  • 9915943
  • 9660941
• Classification
  • Fibronectin type III domain containing
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000180689
• Locus Specific Databases
  • LRG_693

MeSH Data

• Name
  In Situ Hybridization
• Concept
  Scope note: A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
• Tree numbers
  • E01.370.225.500.620.670.325
  • E01.370.225.750.600.670.325
  • E05.200.500.620.670.325
  • E05.200.750.600.670.325
  • E05.393.661.475
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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