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Also known as
Nephrin
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Other names
nephrin; Nephrin; nephrin; renal glomerulus-specific cell adhesion receptor; nephrosis 1, congenital, Finnish type (nephrin); Renal glomerulus-specific cell adhesion receptor
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
NPHS1; NPHS1; CNF; NPHN; nephrin; NPHN
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Gene name synonims
NPHS1; NPHS1; CNF; NPHN; nephrin; NPHN
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Other gene names
NPHS1; NPHS1; CNF; NPHN; nephrin; NPHN
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Clonality
Monoclonal
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Immunoglobulin isotype
IgM,k
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Clone
174CT2.1.1
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Human; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by Protein G affinity chromatography.
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Form Appearance
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applications
ELISA (EL/EIA), Western Blot (WB)
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Description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Nephrin, CT (NPHN, CNF, Nephrosis 1 Congenital Finnish , NPHS1, Renal Glomerulus-specific Adhesion Receptor). For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
NPHS1
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Short name
Nephrin, CT (NPHN, CNF, Nephrosis 1 Congenital Finnish , NPHS1, Renal Glomerulus-specific Adhesion Receptor)
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Alternative name
Anti-Nephrin, CT (NPHN, CNF, Nephrosis 1 Congenital Finnish Type, NPHS1, Renal Glomerulus-specific Cell Adhesion Receptor)
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Alternative to gene target
nephrosis 1, congenital, Finnish type (nephrin), CNF and nephrin and NPHN, NPHS1 and IDBG-45496 and ENSG00000161270 and 4868, alpha-actinin binding, Plasma membranes, Nphs1 and IDBG-169263 and ENSMUSG00000006649 and 54631, NPHS1 and IDBG-636002 and ENSBTAG00000007821 and 519706
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Tissue
cell
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Disease
congenital
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