NALP3 (NACHT-, LRR- and PYD-Containing Protein 3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein, PYPAF1, PYRIN-Containing APAF1-like Protein 1, CIAS1)

• Catalog number
  MBS604215
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [NALP3]
• Products_name_syn
  [Anti -NALP3 (NACHT-, LRR- and PYD-Containing Protein 3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein, PYPAF1, PYRIN-Containing APAF1-like Protein 1, CIAS1)]
• Other_names
  [NACHT, LRR and PYD domains-containing protein 3 isoform d; AII/AVP receptor-like; NACHT, LRR and PYD domains-containing protein 3; cryopyrin; OTTHUMP00000038408; OTTHUMP00000038409; OTTHUMP00000038410; OTTHUMP00000038411; OTTHUMP00000230825; caterpiller protein 1.1; PYRIN-containing APAF1-like protein 1; NACHT, LRR and PYD containing protein 3; cold autoinflammatory syndrome 1 protein; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; NLR family, pyrin domain containing 3]
• Other_gene_names
  [NLRP3; CIAS1; AII; AVP; FCU; MWS; FCAS; CIAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL; FLJ95925]
• Clonality
  Monoclonal
• Clone
  [6D600]
• Reactivity
  Human
• Specificity
  Recognizes endogenous human NALP3 by Immunoprecipitation and Western Blot.
• Purity
  Highly Purified Purified from concentrated hybridoma tissue culture supernatant. 95% (SDS-PAGE).
• Form
  Supplied as a liquid in PBS containing 0.02% sodium azide.
• Concentration
  1 mg/mL.
• Storage_stability
  May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Suitable for use in Western Blot, Immunoprecipitation and immunohistochemistry. Other applications have not been tested.

• Gene target
  NALP3   NACHT   LRR   PYD   Protein   Cryopyrin   Cold   Autoinflammatory   Syndrome   Protein   PYPAF1   PYRIN   APAF1-like   Protein   CIAS1  
• Gene symbol
  APAF1, NLRP3, LRR1, NLRP14
• Short name
  NALP3 (NACHT-, LRR- PYD- Protein 3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein, PYPAF1, PYRIN- APAF1-like Protein 1, CIAS1)
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  NALP3 (NACHT-, LRR- and PYD-Containing Protein 3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein, PYPAF1, PYRIN-Containing apoptotic peptidase activating factor 1-like Protein 1, CIAS1)
• Alternative to gene target
  apoptotic peptidase activating factor 1, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, ADP binding, nuclei, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782
• Disease
  syndrome

Gene info

• Identity
  HGNC:576
• Gene
  APAF1
• Long gene name
  apoptotic peptidase activating factor 1
• Synonyms gene name
  • apoptotic protease activating factor
  • apoptotic peptidase activating factor
• Synonyms
  • CED4
  • APAF-1
• GenBank acession
  • AF013263
• Locus
  12q23.1
• Discovery year
  1998-01-20
• Entrez gene record
  317
• Pubmed identfication
  • 9267021
  • 10702682
• RefSeq identity
  • NM_181861.1
• Classification
  • Apoptosome
  • WD repeat domain containing
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000170214

Gene info

• Identity
  HGNC:16400
• Gene
  NLRP3
• Long gene name
  NLR family pyrin domain containing 3
• Synonyms gene
  • C1orf7
  • CIAS1
  • DFNA34
• Synonyms gene name
  • cold autoinflammatory syndrome 1
  • deafness, autosomal dominant 34
• Synonyms
  • AGTAVPRL
  • AII
  • AVP
  • FCAS
  • FCU
  • NALP3
  • PYPAF1
  • MWS
  • CLR1.1
• Synonyms name
  • Cryopyrin
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
• GenBank acession
  • AF054176
• Locus
  1q44
• Discovery year
  2001-08-28
• Entrez gene record
  114548
• Pubmed identfication
  • 10741953
• RefSeq identity
  • NM_004895
• Classification
  • Pyrin domain containing
  • NLR family
• VEGA ID
  OTTHUMG00000040647
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_197

Gene info

• Identity
  HGNC:19742
• Gene
  LRR1
• Long gene name
  leucine rich repeat protein 1
• Synonyms gene
  • PPIL5
• Synonyms gene name
  • peptidylprolyl isomerase (cyclophilin)-like 5
• Synonyms
  • MGC20689
  • LRR-1
• Synonyms name
  • LRR-repeat protein 1
• GenBank acession
  • BC030142
• Locus
  14q21.3
• Discovery year
  2002-11-20
• Entrez gene record
  122769
• Pubmed identfication
  • 11804328
  • 21074724
• RefSeq identity
  • NM_203467
• Classification
  • Cyclophilin peptidylprolyl isomerases
• VEGA ID
  OTTHUMG00000140273

Gene info

• Identity
  HGNC:22939
• Gene
  NLRP14
• Long gene name
  NLR family pyrin domain containing 14
• Synonyms gene
  • NALP14
• Synonyms gene name
  • NACHT, leucine rich repeat and PYD containing 14
• Synonyms
  • NOD5
  • GC-LRR
  • Nalp-iota
  • PAN8
  • CLR11.2
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14
• GenBank acession
  • BK001107
• Locus
  11p15.4
• Discovery year
  2003-10-28
• Entrez gene record
  338323
• Pubmed identfication
  • 12563287
• RefSeq identity
  • NM_176822
• Classification
  • NLR family
  • Pyrin domain containing
• VEGA ID
  OTTHUMG00000165508

MeSH Data

• Name
  Cryopreservation
• Concept
  Scope note: Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
• Tree numbers
  • E01.370.225.500.620.760.160
  • E01.370.225.750.600.760.160
  • E02.792.156
  • E05.200.500.620.760.160
  • E05.200.750.600.760.160
  • E05.760.156
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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