PIASy, NT (PIAS4, PIASG, E3 SUMO-protein ligase PIAS4, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma)

• Catalog number
  MBS646078
• Price
  Please ask
• Size
  5x0.2 mL

• Products_type
  Antibody
• Products_short_name
  [PIASy]
• Products_name_syn
  [Anti -PIASy, NT (PIAS4, PIASG, E3 SUMO-protein ligase PIAS4, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma)]
• Other_names
  [PIAS4 protein; E3 SUMO-protein ligase PIAS4; E3 SUMO-protein ligase PIAS4; PIAS-gamma; zinc finger, MIZ-type containing 6; protein inhibitor of activated STAT protein 4; protein inhibitor of activated STAT protein PIASy; protein inhibitor of activated STAT protein gamma; protein inhibitor of activated STAT, 4; PIASy; Protein inhibitor of activated STAT protein 4; Protein inhibitor of activated STAT protein gamma]
• Other_gene_names
  [PIAS4; PIAS4; PIASY; Piasg; ZMIZ6; PIASG; PIAS-gamma]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Human
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.

• Gene target
  PIASy   PIAS4   PIASG   SUMO-protein   ligase   PIAS4   PIASy   Protein   inhibitor   activated   STAT   protein   Protein   inhibitor   activated   STAT   protein   gamma  
• Gene symbol
  PIAS4, STAT6, SOAT1, SUMO1
• Short name
  PIASy, NT (PIAS4, PIASG, E3 SUMO-protein ligase PIAS4, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  PIASy, NT (PIAS4, PIASG, E3 SUMO-protein ligase PIAS4, PIASy, Protein suppressor on activated Signal transducer and activation on transcription protein 4, Protein suppressor on activated Signal transducer and activation on transcription protein g)

Gene info

• Identity
  HGNC:17002
• Gene
  PIAS4
• Long gene name
  protein inhibitor of activated STAT 4
• Synonyms
  • Piasg
  • PIASY
  • FLJ12419
  • ZMIZ6
• Synonyms name
  • zinc finger, MIZ-type containing 6
• GenBank acession
  • AF077952
• Locus
  19p13.3
• Discovery year
  2004-06-02
• Entrez gene record
  51588
• Pubmed identfication
  • 9724754
• RefSeq identity
  • NM_015897
• Classification
  • Zinc fingers MIZ-type
• VEGA ID
  OTTHUMG00000181759

Gene info

• Identity
  HGNC:11368
• Gene
  STAT6
• Long gene name
  signal transducer and activator of transcription 6
• Synonyms gene name
  • signal transducer and activator of transcription 6, interleukin-4 induced
• Synonyms
  • D12S1644
  • IL-4-STAT
• GenBank acession
  • BC005823
  • BQ028928
• Locus
  12q13.3
• Discovery year
  1995-11-09
• Entrez gene record
  6778
• Pubmed identfication
  • 9605853
  • 8085155
• RefSeq identity
  • NM_003153
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000171194
• Locus Specific Databases
  • LRG_1369

Gene info

• Identity
  HGNC:11177
• Gene
  SOAT1
• Long gene name
  sterol O-acyltransferase 1
• Synonyms gene
  • SOAT
  • STAT
• Synonyms gene name
  • sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1
• Synonyms
  • ACAT
  • ACAT1
• Synonyms name
  • acyl-Coenzyme A: cholesterol acyltransferase
• GenBank acession
  • L21934
• Locus
  1q25.2
• Discovery year
  1998-11-04
• Entrez gene record
  6646
• Pubmed identfication
  • 8407899
• RefSeq identity
  • NM_003101
• VEGA ID
  OTTHUMG00000035253

Gene info

• Identity
  HGNC:12502
• Gene
  SUMO1
• Long gene name
  small ubiquitin like modifier 1
• Synonyms gene
  • UBL1
• Synonyms gene name
  • ubiquitin-like 1 (sentrin)
  • SMT3 suppressor of mif two 3 homolog 1 (yeast)
  • SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
• Synonyms
  • PIC1
  • GMP1
  • SMT3C
  • SUMO-1
  • SMT3H3
  • OFC10
• GenBank acession
  • U38784
• Locus
  2q33.1
• Discovery year
  1996-06-04
• Entrez gene record
  7341
• Pubmed identfication
  • 8812453
  • 8906799
• RefSeq identity
  • NM_003352
• VEGA ID
  OTTHUMG00000132839

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products