Mouse Monoclonal [clone E11] (IgG1) to Human CR1 / CD35
-
Catalog numberMBS245363
-
PricePlease ask
-
Size0.05 mg
-
-
Products_typeAntibody
-
Products_short_name[CR1 / CD35]
-
Products_name_syn[Anti-CR1 / CD35 Antibody (clone E11, Azide-free) IHC-plus; CR1; C3b/C4b receptor; C3-binding protein; CD35; C3BR; Knops blood group antigen; C4BR; CD35 antigen; Complement receptor type 1; KN; Human CR1; CD35]
-
Other_names[complement receptor type 1 isoform S; Complement receptor type 1; complement receptor type 1; CD35 antigen; C3b/C4b receptor; C3-binding protein; Knops blood group antigen; complement component (3b/4b) receptor 1 (Knops blood group); C3b/C4b receptor; CD_antigen: CD35]
-
Products_gene_name[CR1]
-
Products_gene_name_syn[CD35]
-
Other_gene_names[CR1; CR1; KN; C3BR; C4BR; CD35; C3BR]
-
ClonalityMonoclonal
-
Clone[E11]
-
ReactivityCynomolgus monkey, Rhesus monkey, Baboon, Human
-
SpecificityIs a single chain cell surface glycoprotein which exists in four allotypic forms (A, B, C, D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement. Clone E11 has been reported to be suitable for use in Western Blot.
-
PurityProtein A Purified
-
FormPBS, pH 7.4. Sourced in TCS.
-
Concentration1 mg/ml
-
Storage_stability+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
-
Tested_applicationImmunohistochemistry (IHC - Paraffin; IHC - Frozen), Flow Cytometry (FC/FACS)
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus
-
Gene target
-
Gene symbolCR1
-
Short nameMouse Monoclonal [clone E11] (IgG1) CR1 / CD35
-
TechniqueMouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
-
HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
-
IsotypeIgG1, IgG1
-
SpeciesHuman, Humans, Mouses
-
Alternative nameMouse monoclonal [clonality E11] (IgG1) to H. sapiens complement component (3b/4b) receptor 1 (Knops blood group) / CD35
-
Alternative techniquemurine
-
Alternative to gene targetcomplement component (3b/4b) receptor 1 (Knops blood group), C3BR and C4BR and CD35 and KN, CR1 and IDBG-106358 and ENSG00000203710 and 1378, complement component C3b receptor activity, Cell surfaces
-
Clone nameE11
-
Gene info
-
Identity
-
Gene
-
Long gene namecomplement C3b/C4b receptor 1 (Knops blood group)
-
Synonyms gene name
- complement component (3b/4b) receptor 1, including Knops blood group system
- complement component (3b/4b) receptor 1 (Knops blood group)
- complement component 3b/4b receptor 1 (Knops blood group)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Blood group antigens
- Complement system regulators and receptors
- CD molecules
- Sushi domain containing
-
VEGA ID
-
Locus Specific Databases