MOUSE ANTI DIPHTHERIA TOXIN A
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Catalog numberMBS211588
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Price:
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Size0.1 mg
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Products_typeAntibody
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Products_short_name[DIPHTHERIA TOXIN A]
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Other_names[diphtheria toxin A]
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ClonalityMonoclonal
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Clone[8G2]
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SpecificityThis item recognises diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kDa, it is then processed to form A and B fragments both of which appear to be required for toxicity. This item recognises both the free and bound A subunit of diphtheria toxin.
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FormPurified Purified IgG - liquid
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ConcentrationIgG concentration 0.1 mg/ml
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Storage_stabilityStore at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_applicationELISA (EIA)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Short nameMOUSE ANTI DIPHTHERIA A
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TechniqueMouse, anti, antibody to, mouses
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HostMouse
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IsotypeIgG1
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SpeciesMouse, Mouses
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Alternative nameMOUSE antibody to DIPHTHERIA TOXIN A
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Alternative techniquemurine, antibodies
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MeSH Data
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Name
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ConceptScope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
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Tree numbers
- E01.370.225.812.735.830
- E05.200.812.735.830
- E05.478.566.380.810
- E05.478.566.639.810
- E05.478.594.760.830
- E05.601.470.380.810
- E05.601.470.639.810
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Qualifiersethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data