MOUSE ANTI DIPHTHERIA TOXIN

• Catalog number
  MBS211587
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [DIPHTHERIA TOXIN]
• Other_names
  [diphtheria toxin; diphtheria toxin]
• Other_gene_names
  [tox]
• Clonality
  Monoclonal
• Clone
  [8G1]
• Specificity
  This item recognises diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kDa, it is then processed to form A and B fragments both of which appear to be required for toxicity. This item is specific for the intact toxin/toxoid and does not react with free A or B subunits.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.1 mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  ELISA (EIA)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  DIPHTHERIA  
• Gene symbol
  HBEGF
• Short name
  MOUSE ANTI DIPHTHERIA
• Technique
  Mouse, anti, antibody to, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Mouse, Mouses
• Alternative name
  MOUSE antibody to DIPHTHERIA TOXIN
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:3059
• Gene
  HBEGF
• Long gene name
  heparin binding EGF like growth factor
• Synonyms gene
  • HEGFL
  • DTS
  • DTR
• Synonyms gene name
  • diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)
  • heparin-binding EGF-like growth factor
• Synonyms name
  • Diphtheria toxin receptor (heparin-binding EGF-like growth factor)
  • heparin-binding epidermal growth factor
• Locus
  5q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  1839
• Pubmed identfication
  • 7590736
  • 12163414
• RefSeq identity
  • NM_001945
• VEGA ID
  OTTHUMG00000129496

MeSH Data

• Name
  Radioimmunosorbent Test
• Concept
  Scope note: Radioimmunoassay of proteins using antibody coupled to an immunosorbent.
• Tree numbers
  • E05.478.566.380.830
  • E05.478.566.639.830
  • E05.601.470.380.830
  • E05.601.470.639.830
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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