MLH1 (Human Mul L Homolog, Familial Nonpolyposis Colin Cancer Type 2, COCA2, Colon Cancer Type 2, DNA Mismatch Repair Protein Mlh1, FCC2, hMLH1, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis Type 2, MutL Protein Homolog
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Catalog numberMBS604431
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Price746.49 USD
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Size0.1 mg
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Products_typeAntibody
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Products_short_name[MLH1]
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Products_name_syn[Anti -MLH1 (Human Mul L Homolog, Familial Nonpolyposis Colin Cancer Type 2, COCA2, Colon Cancer Type 2, DNA Mismatch Repair Protein Mlh1, FCC2, hMLH1, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis Type 2, MutL Protein Homolog]
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Other_names[Mlh1; CG11482 gene product from transcript CG11482-RA; Mlh1; CG11482-PA; Mlh1-PA]
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Other_gene_names[Mlh1; CG11482; DmelCG11482; dmlh-1; dmlh1]
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ClonalityMonoclonal
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Clone[8L781]
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ReactivityHuman
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SpecificityIn Molt-4, a 83kD band is observed. Species Crossreactivity: Human.
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PurityAffinity Purified Purified by immunoaffinity chromatography.
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FormPBS containing 0.2% gelatin, 0.05% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationWestern Blot (WB)
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolMLH1, MSH2, PRKDC, HLA-DOA
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Short nameMLH1 ( Mul L Homolog, Familial Nonpolyposis Colin Cancer 2, COCA2, Colon Cancer 2, DNA Mismatch Repair Protein Mlh1, FCC2, hMLH1, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis 2, MutL Protein Homolog
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Techniquedna
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HostMouse
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IsotypeIgG
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SpeciesHuman, Humans
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Alternative namemutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (H. sapiens Mul L Homolog, Familial Nonpolyposis Colin Cancer classification 2, COCA2, Colon Cancer classification 2, Desoxyribonucleic acid Mismatch Repair Protein mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), FCC2, hMLH1, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis classification 2, MutL Protein Homolog
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Alternative to gene targetmutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), COCA2 and FCC2 and hMLH1 and HNPCC and HNPCC2, MLH1 and IDBG-24600 and ENSG00000076242 and 4292, structure-specific DNA binding, nuclei, Mlh1 and IDBG-202755 and ENSMUSG00000032498 and 17350, MLH1 and IDBG-644253 and ENSBTAG00000016758 and 533652
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Tissuecolon
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Diseasecancer
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Gene info
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Identity
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Gene
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Long gene namemutL homolog 1
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Synonyms gene
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Synonyms gene name
- mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2)
- mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-11-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MutL homologs
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemutS homolog 2
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Synonyms gene
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Synonyms gene name
- mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)
- mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-07-28
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Entrez gene record
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Pubmed identfication
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Classification
- MutS homologs
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameprotein kinase, DNA-activated, catalytic subunit
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Synonyms gene
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Synonyms gene name
- protein kinase, DNA-activated, catalytic polypeptide
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Armadillo like helical domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DO alpha
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
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Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
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Qualifierslegislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data