Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T cell Specific Transcription Factor 1 alpha, TCF1 alpha)

  • Catalog number
    MBS600490
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [Lymphoid Enhancer Factor 1]
  • Products_name_syn
    [Anti -Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T cell Specific Transcription Factor 1 alpha, TCF1 alpha)]
  • Other_names
    [lymphoid enhancer-binding factor 1 isoform 1; Lymphoid enhancer-binding factor 1; lymphoid enhancer-binding factor 1; TCF1-alpha; T cell-specific transcription factor 1-alpha; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha]
  • Other_gene_names
    [LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha]
  • Clonality
    Monoclonal
  • Clone
    [6D538]
  • Reactivity
    Human, Mouse
  • Specificity
    Recognizes human and mouse LEF. Does not cross-react with T cell factor 3 (TCF3) or T cell factor 4 (TCF4). Detects a band of ~68kDa by Western blot.
  • Purity
    Highly Purified Purified by size exclusion chromatography.
  • Form
    Supplied as a liquid in PBS, 0.1% sodium azide, PEG and sucrose, before the addiition of glycerol to 40%.
  • Storage_stability
    May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    Western Blot (WB), Immunocytochemistry (ICC)
  • Description
    The Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T Specific Transcription Factor 1 alpha, TCF1 alpha) is a α- or alpha protein sometimes glycoprotein present in blood. For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene target
    Lymphoid   Enhancer   Factor   LEF1   Lymphoid   Enhancer-binding   Factor   DKFZp586H0919   HGNC   6551   Specific   Transcription   Factor   alpha   TCF1   alpha  
  • Gene symbol
    LEF1-AS1, LEF1, HNF1A
  • Short name
    Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T Specific Transcription Factor 1 alpha, TCF1 alpha)
  • Host
    Mouse
  • Isotype
    IgG1
  • Alternative name
    Lymphoid Enhancer Factor 1 (lymphoid enhancer-binding factor 1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T cellular Specific Transcription Factor 1 a, TCF1 a)
  • Alternative to gene target
    lymphoid enhancer-binding factor 1, LEF1 and IDBG-33529 and ENSG00000138795 and 51176, DNA binding, nuclei, Lef1 and IDBG-194292 and ENSMUSG00000027985 and 16842, LEF1 and IDBG-640560 and ENSBTAG00000006844 and 535399
  • Tissue
    cell
Gene info
Gene info
  • Identity
    HGNC:6551
  • Gene
    LEF1
  • Long gene name
    lymphoid enhancer binding factor 1
  • Synonyms gene name
    • lymphoid enhancer-binding factor 1
  • Synonyms
  • Locus
    4q25
  • Discovery year
    1991-06-05
  • Entrez gene record
    51176
  • Pubmed identfication
  • Classification
    • TCF/LEF transcription factor family
    • Wnt enhanceosome complex
  • VEGA ID
    OTTHUMG00000131809
Gene info
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Lymphoid Enhancer Factor 1 LEF1 Lymphoid Enhancer binding Fa
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