LIGHT, Soluble, Recombinant, Human (HVEML, Tumor Necrosis Factor Ligand Superfamily Member 14, TNFSF14, CD258)
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Catalog numberMBS636097
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Price:
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Size5x0.01 mg
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Products_typeRecombinant Protein
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Products_short_name[LIGHT, Soluble]
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Other_names[LIGHT, partial]
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SpecificityBinds to human and mouse LTbetaR and human HVEM and DcR3.
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PurityHighly Purified>95% (SDS-PAGE)
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FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
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Storage_stabilityShort-term Storage: +4 degree CLong-term Storage: -20 degree CStable for at least 6 months after receipt when stored at -20 degree C.
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolTNFSF14
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Short nameLIGHT, Soluble, Recombinant, (HVEML, Tumor Necrosis Factor Ligand Superfamily Member 14, TNFSF14, CD258)
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TechniqueRecombinant, light, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostHuman, CHO cells
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SpeciesHuman, Humans
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Alternative nameLIGHT, Soluble, Rec., H. sapiens (HVEML, Tumor Necrosis Factor Ligand supergroup Member 14, tumor necrosis factor (ligand) superfamily, member 14, CD258)
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Alternative techniquerec
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Alternative to gene targettumor necrosis factor (ligand) superfamily, member 14, CD258 and HVEML and LIGHT and LTg and TR2, TNFSF14 and IDBG-21748 and ENSG00000125735 and 8740, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, Extracellular, Tnfsf14 and IDBG-193745 and ENSMUSG00000005824 and 50930, BT.64160 and IDBG-643941 and ENSBTAG00000012223 and 505521
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 14
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 14
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data