LIGHT, Soluble, Recombinant, Human (HVEML, Tumor Necrosis Factor Ligand Superfamily Member 14, TNFSF14, CD258)

• Catalog number
  MBS636097
• Price
  Please ask
• Size
  0.01 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [LIGHT, Soluble]
• Other_names
  [LIGHT, partial]
• Specificity
  Binds to human and mouse LTbetaR and human HVEM and DcR3.
• Purity
  Highly Purified>95% (SDS-PAGE)
• Form
  Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
• Storage_stability
  Short-term Storage: +4 degree CLong-term Storage: -20 degree CStable for at least 6 months after receipt when stored at -20 degree C.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  LIGHT   Soluble   HVEML   Tumor   Necrosis   Factor   Ligand   Superfamily   Member   TNFSF14   CD258  
• Gene symbol
  TNFSF14
• Short name
  LIGHT, Soluble, Recombinant, (HVEML, Tumor Necrosis Factor Ligand Superfamily Member 14, TNFSF14, CD258)
• Technique
  Recombinant, light, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Human, CHO cells
• Species
  Human, Humans
• Alternative name
  LIGHT, Soluble, Rec., H. sapiens (HVEML, Tumor Necrosis Factor Ligand supergroup Member 14, tumor necrosis factor (ligand) superfamily, member 14, CD258)
• Alternative technique
  rec
• Alternative to gene target
  tumor necrosis factor (ligand) superfamily, member 14, CD258 and HVEML and LIGHT and LTg and TR2, TNFSF14 and IDBG-21748 and ENSG00000125735 and 8740, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, Extracellular, Tnfsf14 and IDBG-193745 and ENSMUSG00000005824 and 50930, BT.64160 and IDBG-643941 and ENSBTAG00000012223 and 505521
• Tissue
  tumor

Gene info

• Identity
  HGNC:11930
• Gene
  TNFSF14
• Long gene name
  TNF superfamily member 14
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 14
• Synonyms
  • LIGHT
  • LTg
  • HVEM-L
  • CD258
• GenBank acession
  • AF036581
• Locus
  19p13.3
• Discovery year
  1998-12-04
• Entrez gene record
  8740
• Pubmed identfication
  • 9462508
• Classification
  • Tumor necrosis factor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000181835

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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