Leukemia Inhibitory Factor (LIF, Cholinergic Differentiation Factor, CDF, DIA, Differentiation-stimulating Factor, D Factor, HILDA, Melanoma-derived LPL Inhibitor, MLPLI)

• Catalog number
  MBS628697
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Leukemia   Inhibitory   Factor   LIF   Cholinergic   Differentiation   Factor   CDF   DIA   Differentiation-stimulating   Factor   Factor   HILDA   Melanoma-derived   LPL   Inhibitor   MLPLI  
• Gene symbol
  LIF, LIF-AS1, LPL, LIF-AS2, DIAPH2
• Short name
  Leukemia Inhibitory Factor (LIF, Cholinergic Differentiation Factor, CDF, DIA, Differentiation-stimulating Factor, D Factor, HILDA, Melanoma-derived LPL Inhibitor, MLPLI)
• Alternative name
  Leukemia Inhibitory Factor (leukemia inhibitory factor, Cholinergic Differentiation Factor, CDF, DIA, Differentiation-stimulating Factor, D Factor, HILDA, Melanoma-derived lipoprotein lipase suppressor, MLPLI)
• Alternative to gene target
  leukemia inhibitory factor, CDF and DIA and HILDA and MLPLI, LIF and IDBG-3968 and ENSG00000128342 and 3976, growth factor activity, Extracellular, Lif and IDBG-142317 and ENSMUSG00000034394 and 16878, LIF and IDBG-636335 and ENSBTAG00000007424 and 280840
• Virus
  leukemia

Gene info

• Identity
  HGNC:6596
• Gene
  LIF
• Long gene name
  LIF interleukin 6 family cytokine
• Synonyms gene name
  • leukemia inhibitory factor
  • LIF, interleukin 6 family cytokine
• Synonyms
  • CDF
  • DIA
  • HILDA
• Synonyms name
  • differentiation inhibitory activity
  • differentiation-inducing factor
  • hepatocyte-stimulating factor III
  • cholinergic differentiation factor
  • human interleukin in DA cells
• Locus
  22q12.2
• Discovery year
  1989-06-11
• Entrez gene record
  3976
• Pubmed identfication
  • 1714745
  • 8058719
• RefSeq identity
  • NM_002309
• Classification
  • Receptor ligands
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000150910
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:53473
• Gene
  LIF-AS1
• Long gene name
  LIF antisense RNA 1
• Synonyms
  • Lnc-LIF-AS
• Locus
  22q12.2
• Discovery year
  2017-04-28
• Pubmed identfication
  • 28391028
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6677
• Gene
  LPL
• Long gene name
  lipoprotein lipase
• Synonyms gene
  • LIPD
• Locus
  8p21.3
• Discovery year
  2001-06-22
• Entrez gene record
  4023
• Pubmed identfication
  • 3823907
  • 3597382
  • 3692485
• Classification
  • Lipases
• VEGA ID
  OTTHUMG00000036645
• Locus Specific Databases
  • LRG_1298

Gene info

• Identity
  HGNC:28298
• Gene
  LIF-AS2
• Long gene name
  LIF antisense RNA 2
• Locus
  22q12.2
• Discovery year
  2020-10-07
• Entrez gene record
  91370
• RefSeq identity
  • NR_148946
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:2877
• Gene
  DIAPH2
• Long gene name
  diaphanous related formin 2
• Synonyms gene name
  • diaphanous (Drosophila, homolog) 2
  • diaphanous homolog 2 (Drosophila)
• Synonyms
  • POF
  • DIA
  • POF2
  • DIA2
• Synonyms name
  • Premature ovarian failure 2A
• GenBank acession
  • Y15909
• Locus
  Xq21.33
• Discovery year
  1998-03-17
• Entrez gene record
  1730
• Pubmed identfication
  • 9360932
• RefSeq identity
  • NM_006729
  • NM_007309
• Classification
  • Formins
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000022689
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Mammary Neoplasms, Experimental
• Concept
  Scope note: Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.
• Tree numbers
  • C04.588.531.500
  • C04.619.590
  • E05.598.500.496.843
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, secondary, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, chemistry, psychology, urine, virology, history, blood supply, classification, economics, embryology, genetics, nursing, radiotherapy, prevention & control, pathology, ultrastructure, metabolism, complications, surgery

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