La/SS-B Antigen, Rabbit Thymus

Products_type

Antigen
Products_short_name

[La/SS-B Antigen, Rabbit Thymus]
Purity

Purified by a combination of protein fractionation and column chromatography. Most contaminating antigens have been removed by immunoadsorbent methodology.
Form

Supplied as a lyophilized powder. Reconstitute with 1 mL cold sterile distilled water. Some precipitate may occur but will not affect product performance. Do not store diluted antigen.
Concentration

~10 mg/mL (after reconstitution)
Storage_stability

Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile distilled water. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

ELISA (EL/EIA), Western Blot (WB)
Description

Antigens are peptides or recombinant or native dependent on the production method.
About

Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name

Oryctolagus cuniculus

Identity

HGNC:11316
Gene

SSB
Long gene name

small RNA binding exonuclease protection factor La
Synonyms gene name
- Sjogren syndrome antigen B (autoantigen La)
- Sjogren syndrome antigen B
Synonyms
- LARP3
- La
- La/SSB
Synonyms name
Locus

2q31.1
Discovery year

1990-09-10
Entrez gene record

6741
Pubmed identfication
- 2468131
- 1692037
- 28782243
RefSeq identity
- NM_003142
Classification
- La ribonucleoproteins
- RNA binding motif containing
VEGA ID

OTTHUMG00000132212

Identity

HGNC:4703
Gene

GYPB
Long gene name

glycophorin B (MNS blood group)
Synonyms gene
- MNS
Synonyms gene name
- glycophorin B (includes Ss blood group)
- glycophorin B (Ss blood group)
Synonyms
- GPB
- SS
- CD235b
Locus

4q31.21
Discovery year

1988-08-31
Entrez gene record

2994
RefSeq identity
- NM_002100
Classification
- Blood group antigens
- CD molecules
VEGA ID

OTTHUMG00000161404
Locus Specific Databases
- Blood Group Antigen Mutation Database
- LRG_794

Identity

HGNC:11153
Gene

SNRPB
Long gene name

small nuclear ribonucleoprotein polypeptides B and B1
Synonyms gene
- SNRPB1
Synonyms
- COD
- SmB/SmB'
- Sm-B/B'
- snRNP-B
Locus

20p13
Discovery year

1988-11-28
Entrez gene record

6628
Pubmed identfication
- 1376292
Classification
- Small nucleolar RNA protein coding host genes
- Sm spliceosomal proteins
VEGA ID

OTTHUMG00000031694

Identity

HGNC:3424
Gene

ERAL1
Long gene name

Era like 12S mitochondrial rRNA chaperone 1
Synonyms gene name
- Era (E. coli G-protein homolog)-like 1
- Era G-protein-like 1 (E. coli)
- Era-like 12S mitochondrial rRNA chaperone 1
Synonyms
- HERA-B
GenBank acession
- AF082657
Locus

17q11.2
Discovery year

1999-11-19
Entrez gene record

26284
Pubmed identfication
- 10945472
- 20604745
VEGA ID

OTTHUMG00000132675

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data