IGF BP1 protein[IGF BP1]

Products_type

Recombinant Protein
Products_gene_name

[IGF BP1]
Description

IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.

Gene target

BP1 protein[ BP1]
Gene symbol

SIGMAR1, REXO1, EIF4EBP1, DLX4, GORAB, ATF2, NAE1, SIGLEC6, TSPOAP1
Short name

IGF BP1 protein[IGF BP1]
Technique

IGF, igfs
Host

Human
Alternative name

IGF BP1 protein[IGF BP1]
Alternative technique

igfs

Identity

HGNC:24616
Gene

REXO1
Long gene name

RNA exonuclease 1 homolog
Synonyms gene
- TCEB3BP1
Synonyms gene name
- transcription elongation factor B polypeptide 3 binding protein 1
- REX1, RNA exonuclease 1 homolog (S. cerevisiae)
Synonyms
- EloA-BP1
- KIAA1138
Synonyms name
- elongin A binding protein 1
GenBank acession
- AB032964
Locus

19p13.3
Discovery year

2004-01-16
Entrez gene record

57455
Pubmed identfication
- 10574461
RefSeq identity
- NM_020695
Classification
- MicroRNA protein coding host genes
- Exonucleases
VEGA ID

OTTHUMG00000179991

Identity

HGNC:3288
Gene

EIF4EBP1
Long gene name

eukaryotic translation initiation factor 4E binding protein 1
Synonyms
- PHAS-I
- 4E-BP1
Synonyms name
- phosphorylated heat- and acid-stable protein regulated by insulin 1
Locus

8p11.23
Discovery year

1996-10-26
Entrez gene record

1978
Pubmed identfication
- 7935836
RefSeq identity
- NM_004095
VEGA ID

OTTHUMG00000164012

Identity

HGNC:784
Gene

ATF2
Long gene name

activating transcription factor 2
Synonyms gene
- CREB2
Synonyms gene name
- cAMP responsive element binding protein 2
Synonyms
- TREB7
- CRE-BP1
- HB16
GenBank acession
- X15875
Locus

2q31.1
Discovery year

1991-08-01
Entrez gene record

1386
Pubmed identfication
- 1833307
- 1838349
RefSeq identity
- NM_001880
Classification
- Basic leucine zipper proteins
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000132424

Identity

HGNC:10875
Gene

SIGLEC6
Long gene name

sialic acid binding Ig like lectin 6
Synonyms gene
- CD33L
- CD33L1
Synonyms gene name
- sialic acid binding Ig-like lectin 6
Synonyms
- OB-BP1
- SIGLEC-6
- CD327
GenBank acession
- D86358
Locus

19q13.41
Discovery year

1996-12-17
Entrez gene record

946
Pubmed identfication
- 9465907
RefSeq identity
- NM_001245
Classification
- I-set domain containing
- Sialic acid binding Ig like lectins
- V-set domain containing
- CD molecules
VEGA ID

OTTHUMG00000133571