Human Myeloma IgE

• Catalog number
  MBS318250
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [IgE, kappa and lambda]
• Products_name_syn
  [Human Myeloma Immunoglobulin E (IgE), kappa and lambda]
• Reactivity
  Human
• Specificity
  IgE, kappa and lambda
• Purity
  >=99% pure (SDS-PAGE)
• Form
  Purified, Liquid
• Concentration
  Total protein: 3.5mg/ml (Lowry) Activity: 1,120,000IU/ml (Bayer ACS:180 calibrated against WHO 2nd IRP 75/502)
• Storage_stability
  Short term store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple freeze/thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.

• Gene target
  Myeloma  
• Gene symbol
  MYEOV, COPS9, C1orf35
• Short name
  Myeloma IgE
• Technique
  IgE, IgEs
• Host
  Human myeloma
• Isotype
  IgE, IgE
• Species
  Human, Humans
• Alternative name
  H. sapiens Myeloma immunoglobuline E
• Alternative technique
  immunoglobulin-e

Gene info

• Identity
  HGNC:7563
• Gene
  MYEOV
• Long gene name
  myeloma overexpressed
• Synonyms gene name
  • myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
• Synonyms
  • OCIM
• GenBank acession
  • AJ223366
• Locus
  11q13.3
• Discovery year
  1999-12-02
• Entrez gene record
  26579
• Pubmed identfication
  • 10753852
• VEGA ID
  OTTHUMG00000167836

Gene info

• Identity
  HGNC:21314
• Gene
  COPS9
• Long gene name
  COP9 signalosome subunit 9
• Synonyms gene
  • MYEOV2
• Synonyms gene name
  • myeloma overexpressed 2
• Synonyms
  • CSNAP
• Synonyms name
  • CSN acidic protein
• GenBank acession
  • AF453951
• Locus
  2q37.3
• Discovery year
  2005-06-24
• Entrez gene record
  150678
• Pubmed identfication
  • 23776465
  • 26456823
• RefSeq identity
  • NM_138336
• VEGA ID
  OTTHUMG00000133352

Gene info

• Identity
  HGNC:19032
• Gene
  C1orf35
• Long gene name
  chromosome 1 open reading frame 35
• Synonyms
  • MGC4174
  • MMTAG2
• Synonyms name
  • multiple myeloma tumor-associated protein 2
• GenBank acession
  • AY137773
• Locus
  1q42.13
• Discovery year
  2002-08-19
• Entrez gene record
  79169
• Pubmed identfication
  • 12545221
  • 32103167
• RefSeq identity
  • NM_024319
• VEGA ID
  OTTHUMG00000037793

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