Rat IgE Kappa (min X other Rat Ig's), Clone: IR2, Myeloma
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Catalog numberYULIR2b-10
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Price:
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Size10 ml
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Alternative name 1Rat IgE Kappa (min X other Rat Ig's), Clone: IR2, Myeloma
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Alternative name 2Rat IgE Kappa (min X other Rat Ig's), Clone: IR2, Myeloma
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Alternative name 3Rattus norvegicus IgE Kappa (min X other Rattus norvegicus Ig's), Clone: IR2, Myeloma
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Alternative name 4anti- IgE Kappa min X other Ig's Clone: IR2 Myeloma
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Alternative name 5IgE Kappa min X other Ig's Clone: IR2 Myeloma
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ClonalityMonoclonal Antibody
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DescriptionThis is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.
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Storage and handlingGenerally, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for longer periods - at -20 . Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°C.
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AdvisoryTo keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
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PropertiesImmunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameRattus norvegicus
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Gene target
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Short nameIgE Kappa (min X other Ig's), Clone: IR2, Myeloma
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TechniqueIgE, IgEs
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HostRat
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IsotypeIgE, IgE
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SpeciesRat, Rats
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Alternative nameRat immunoglobuline E Kappa (min X other Rat Ig's), clonality: IR2, Myeloma
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Alternative techniqueimmunoglobulin-e
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