Hepatocyte Growth Factor Activator Inhibitor 1 (HAI-1, Serine Protease Inhibitor Kunitz-Type I, SPINT1) (Biotin)
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Catalog numberMBS603498
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PricePlease ask
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Size5x0.25 mg
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Products_typeAntibody
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Products_short_name[Hepatocyte Growth Factor Activator Inhibitor 1]
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Products_name_syn[Anti -Hepatocyte Growth Factor Activator Inhibitor 1 (HAI-1, Serine Protease Inhibitor Kunitz-Type I, SPINT1) (Biotin)]
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Other_names[hepatocyte growth factor activator inhibitor 1B; Kunitz-type protease inhibitor 1; kunitz-type protease inhibitor 1; HAI-1; serine protease inhibitor, Kunitz type 1; hepatocyte growth factor activator inhibitor type 1; serine peptidase inhibitor, Kunitz type 1; Hepatocyte growth factor activator inhibitor type 1]
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Other_gene_names[SPINT1; SPINT1; HAI; HAI1; MANSC2; HAI1; HAI-1]
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ClonalityMonoclonal
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Clone[8H110]
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ReactivityHuman
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SpecificityRecognizes human HAI-1 ectodomain.
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PurityPurified Purified
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FormSupplied as a lyophilized powder from PBS, 50ug of bovine serum albumin (BSA) per 1ug of antibody. Labeled with Biotin. Reconstitute with 200ul 40-50% glycerol, PBS.
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Storage_stabilityLyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationELISA (EL/EIA)
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PropertiesBiotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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ConjugationBiotinylated
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
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Gene target
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Gene symbolSPINT1, SPINT2, SPINT1-AS1, ST14, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
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Short nameHepatocyte Growth Factor Activator Inhibitor 1 (HAI-1, Serine Protease Inhibitor Kunitz- I, SPINT1) ( )
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HostMouse
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IsotypeIgG1
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LabelBiotin
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Alternative nameHepatocyte Growth Factor Activator suppressor 1 (HAI-1, Serine Protease suppressor Kunitz-classification I, SPINT1) (biotinilated)
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Gene info
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Identity
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Gene
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Long gene nameserine peptidase inhibitor, Kunitz type 1
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Synonyms gene name
- serine protease inhibitor, Kunitz type 1
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Synonyms
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Locus
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Discovery year1988-07-18
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameserine peptidase inhibitor, Kunitz type 2
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Synonyms gene name
- serine protease inhibitor, Kunitz type, 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-07-23
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSPINT1 antisense RNA 1
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Synonyms
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Locus
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Discovery year2017-03-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameST14 transmembrane serine protease matriptase
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Synonyms gene
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Synonyms gene name
- suppression of tumorigenicity 14 (colon carcinoma)
- suppression of tumorigenicity 14
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-05-05
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Entrez gene record
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Pubmed identfication
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Classification
- Type II transmembrane serine proteases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family