Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha]
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Catalog numberMBS626298
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Price5.43 USD
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SizeNA
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Products_typeAntibody
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ReactivityHuman
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DescriptionThe Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha] is a α- or alpha protein sometimes glycoprotein present in blood. Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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GeneGranulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
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Gene target
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Gene symbolCSF2RA, CSF2, PPP1R3A, RRAS, DAD1P1, HNRNPR, CLDN4, MC1R, CSF1, CSF3
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Short nameGranulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha]
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HostMouse
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Alternative nameGranulocyte Macrophage Colony Stimulating Factor Receptor, a (Granulocyte-macrophage Colony-stimulating Factor Receptor functionnal sequence a, colony stimulating factor 2 receptor, a, low-affinity (granulocyte-macrophage), GM-CSF-R-a, GMCSFR-a, GMR-a, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, a]
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Alternative to gene targetcolony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CD116 and CDw116 and CSF2R and CSF2RAX and CSF2RAY and CSF2RX and CSF2RY and GM-CSF-R-alpha and GMCSFR and GMR and SMDP4, CSF2RA and IDBG-39400 and ENSG00000198223 and 102725415,1438, protein binding, Extracellular, Csf2ra and IDBG-182098 and ENSMUSG00000059326 and 12982, CSF2RA and IDBG-642291 and ENSBTAG00000045948 and 100336606,511847
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Tissuegranulocyte
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Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 2 receptor subunit alpha
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Synonyms gene
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Synonyms gene name
- colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-07-03
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- Pseudoautosomal region 1
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 2
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Synonyms gene name
- colony stimulating factor 2 (granulocyte-macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein phosphatase 1 regulatory subunit 3A
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Synonyms gene
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Synonyms gene name
- protein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle)
- protein phosphatase 1, regulatory (inhibitor) subunit 3A
- protein phosphatase 1, regulatory subunit 3A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-01-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAS related
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Synonyms gene name
- related RAS viral (r-ras) oncogene homolog
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefender against cell death 1 pseudogene 1
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Synonyms gene
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Synonyms gene name
- defender against cell death 1-like
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Synonyms
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Locus
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Discovery year2007-07-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameheterogeneous nuclear ribonucleoprotein R
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heterogeneous nuclear ribonucleoproteins
- RNA binding motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclaudin 4
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Claudins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemelanocortin 1 receptor
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Synonyms gene name
- melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Melanocortin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 1
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Synonyms gene name
- colony stimulating factor 1 (macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 3
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Synonyms gene
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Synonyms gene name
- chromosome 17 open reading frame 33
- colony stimulating factor 3 (granulocyte)
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
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Tree numbers
- E01.370.225.500.383
- E05.200.500.383
- E05.242.383
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data