Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha]

  • Catalog number
    MBS626298
  • Price
    Please ask
  • Size
    NA
  • Products_type
    Antibody
  • Reactivity
    Human
  • Description
    The Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha] is a α- or alpha protein sometimes glycoprotein present in blood. Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene
    Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
  • Gene target
    Granulocyte   Macrophage   Colony   Stimulating   Factor   Receptor   alpha   Granulocyte-macrophage   Colony-stimulating   Factor   Receptor   Subunit   alpha   CSF2RA   GM-CSF-R-alpha   GMCSFR-alpha   GMR-alpha   CDw116   CD116   CSF2R   CSF2RY   [Granulocyte   Macrophage   Colony   Stimulating   Factor   Receptor   alpha]  
  • Gene symbol
    CSF2RA, CSF2, PPP1R3A, RRAS, DAD1P1, HNRNPR, CLDN4, MC1R, CSF1, CSF3
  • Short name
    Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha]
  • Host
    Mouse
  • Alternative name
    Granulocyte Macrophage Colony Stimulating Factor Receptor, a (Granulocyte-macrophage Colony-stimulating Factor Receptor functionnal sequence a, colony stimulating factor 2 receptor, a, low-affinity (granulocyte-macrophage), GM-CSF-R-a, GMCSFR-a, GMR-a, CDw116, CD116, CSF2R, CSF2RY)[Granulocyte Macrophage Colony Stimulating Factor Receptor, a]
  • Alternative to gene target
    colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CD116 and CDw116 and CSF2R and CSF2RAX and CSF2RAY and CSF2RX and CSF2RY and GM-CSF-R-alpha and GMCSFR and GMR and SMDP4, CSF2RA and IDBG-39400 and ENSG00000198223 and 102725415,1438, protein binding, Extracellular, Csf2ra and IDBG-182098 and ENSMUSG00000059326 and 12982, CSF2RA and IDBG-642291 and ENSBTAG00000045948 and 100336606,511847
  • Tissue
    granulocyte
Gene info
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MeSH Data
  • Name
    Colony-Forming Units Assay
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
  • Tree numbers
    • E01.370.225.500.383
    • E05.200.500.383
    • E05.242.383
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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